CRCGN012_HEPG2_24H:O11 Gene Set
Genes
54 genes differentially expressed following the CRCGN012_HEPG2_24H:O11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
7.49487
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
7.45705
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
6.67973
|
|
E2F2
|
E2F transcription factor 2
|
4.46326
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.30723
|
|
MEST
|
mesoderm specific transcript
|
3.84701
|
|
STIMATE
|
STIM activating enhancer
|
3.30403
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
3.14255
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
3.07092
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.98025
|
|
EVL
|
Enah/Vasp-like
|
2.94955
|
|
HEBP1
|
heme binding protein 1
|
2.89979
|
|
SATB1
|
SATB homeobox 1
|
2.82838
|
|
NOTCH1
|
notch 1
|
2.81229
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.75529
|
|
MOK
|
MOK protein kinase
|
2.68476
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.55985
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.52502
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.43763
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.2862
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.28259
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.21088
|
|
TEX10
|
testis expressed 10
|
2.20905
|
|
H2BC12
|
H2B clustered histone 12
|
2.18663
|
|
MX1
|
MX dynamin-like GTPase 1
|
2.15001
|
|
CSK
|
c-src tyrosine kinase
|
2.13294
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.11175
|
|
STK10
|
serine/threonine kinase 10
|
2.02584
|
|
RRAGA
|
Ras-related GTP binding A
|
2.00917
|
|
RSAD2
|
radical S-adenosyl methionine domain containing 2
|
2.00557
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ADI1
|
acireductone dioxygenase 1
|
-6.32759
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.59182
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.77088
|
|
FASTKD5
|
FAST kinase domains 5
|
-4.67782
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.30616
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-3.98523
|
|
LDHD
|
lactate dehydrogenase D
|
-3.97239
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.66926
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.35582
|
|
GOLT1B
|
golgi transport 1B
|
-3.34742
|
|
WASHC4
|
WASH complex subunit 4
|
-3.10985
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.07285
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-3.03363
|
|
MAP7
|
microtubule-associated protein 7
|
-2.67496
|
|
ZW10
|
zw10 kinetochore protein
|
-2.61661
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.6139
|
|
ZNF586
|
zinc finger protein 586
|
-2.59614
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.48824
|
|
CCNB2
|
cyclin B2
|
-2.32886
|
|
GNAS
|
GNAS complex locus
|
-2.3262
|
|
RNF167
|
ring finger protein 167
|
-2.23841
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.11927
|
|
TCTN1
|
tectonic family member 1
|
-2.09837
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.06889
|
