CRCGN012_HEPG2_24H:O14 Gene Set
Genes
32 genes differentially expressed following the CRCGN012_HEPG2_24H:O14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
8.21529
|
|
MOK
|
MOK protein kinase
|
5.79808
|
|
UBQLN2
|
ubiquilin 2
|
4.94342
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.61761
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.55903
|
|
PRKCH
|
protein kinase C, eta
|
4.5067
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.45186
|
|
CHN1
|
chimerin 1
|
4.06434
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.46314
|
|
LCN2
|
lipocalin 2
|
3.26432
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.97362
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.80567
|
|
TBXA2R
|
thromboxane A2 receptor
|
2.59632
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
2.45881
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.39433
|
|
SIRT3
|
sirtuin 3
|
2.30322
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.15142
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.10199
|
|
NR1H3
|
nuclear receptor subfamily 1, group H, member 3
|
2.09594
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DNM1L
|
dynamin 1-like
|
-4.93797
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-4.89985
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.81113
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.25985
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.93989
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.81905
|
|
CDC20
|
cell division cycle 20
|
-3.49832
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.34939
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.29846
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.28783
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-3.19336
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.86537
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
-2.46729
|
