| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | cyclopentanone oxime 5.15 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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66 genes differentially expressed following the CRCGN012_HEPG2_24H:O16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 8.37486 |
| CSK | c-src tyrosine kinase | 8.26863 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 5.03626 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.79419 |
| UBQLN2 | ubiquilin 2 | 4.57966 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 4.4225 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 4.37789 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.21772 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.08791 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 4.08384 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.04299 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 3.28282 |
| PFKL | phosphofructokinase, liver | 2.98578 |
| JADE2 | jade family PHD finger 2 | 2.82185 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.76271 |
| IFI44L | interferon-induced protein 44-like | 2.72035 |
| TLR4 | toll-like receptor 4 | 2.70345 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 2.65066 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.62779 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.56938 |
| MX2 | MX dynamin-like GTPase 2 | 2.49003 |
| RRAGA | Ras-related GTP binding A | 2.47482 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.45876 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 2.41478 |
| ZNF528 | zinc finger protein 528 | 2.40434 |
| IFI44 | interferon-induced protein 44 | 2.38897 |
| KLHL9 | kelch-like family member 9 | 2.27787 |
| OBI1 | ORC ubiquitin ligase 1 | 2.23089 |
| ZNF222 | zinc finger protein 222 | 2.20031 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 2.16923 |
| IFNGR2 | interferon gamma receptor 2 (interferon gamma transducer 1) | 2.06082 |
| ZNF589 | zinc finger protein 589 | 2.06081 |
| MMP1 | matrix metallopeptidase 1 | 2.05579 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 2.02783 |
| OGFRL1 | opioid growth factor receptor-like 1 | 2.01674 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -5.2391 |
| CCNB2 | cyclin B2 | -5.08397 |
| CCDC86 | coiled-coil domain containing 86 | -4.62423 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.6042 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.57884 |
| ENOPH1 | enolase-phosphatase 1 | -4.55537 |
| UGDH | UDP-glucose 6-dehydrogenase | -4.32575 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.32208 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.30894 |
| ISOC1 | isochorismatase domain containing 1 | -4.29549 |
| TLCD3A | TLC domain containing 3A | -4.2213 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.98993 |
| MAP7 | microtubule-associated protein 7 | -3.90499 |
| YME1L1 | YME1-like 1 ATPase | -3.34643 |
| HMG20B | high mobility group 20B | -2.96177 |
| PCNA | proliferating cell nuclear antigen | -2.87458 |
| REEP5 | receptor accessory protein 5 | -2.81875 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -2.72945 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.67605 |
| CCNB1 | cyclin B1 | -2.52887 |
| EGF | epidermal growth factor | -2.45639 |
| WASHC4 | WASH complex subunit 4 | -2.40246 |
| IPO13 | importin 13 | -2.28212 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | -2.27832 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -2.22407 |
| PAGE4 | P antigen family, member 4 (prostate associated) | -2.17439 |
| TCEA2 | transcription elongation factor A (SII), 2 | -2.16289 |
| GET3 | guided entry of tail-anchored proteins factor 3, ATPase | -2.13522 |
| CD69 | CD69 molecule | -2.11354 |
| ANKRD10 | ankyrin repeat domain 10 | -2.07251 |
| KLK2 | kallikrein-related peptidase 2 | -2.07073 |
