CRCGN012_HEPG2_24H:O18 Gene Set
Genes
57 genes differentially expressed following the CRCGN012_HEPG2_24H:O18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GSTZ1
|
glutathione S-transferase zeta 1
|
7.42265
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.79235
|
|
STIMATE
|
STIM activating enhancer
|
5.08708
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.58587
|
|
HDGFL3
|
HDGF like 3
|
4.16165
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
4.13478
|
|
CSK
|
c-src tyrosine kinase
|
4.00037
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.9626
|
|
MELK
|
maternal embryonic leucine zipper kinase
|
3.57215
|
|
DRAP1
|
DR1-associated protein 1 (negative cofactor 2 alpha)
|
3.50628
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.48608
|
|
KIFBP
|
kinesin family binding protein
|
3.29346
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.25462
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.20743
|
|
JADE2
|
jade family PHD finger 2
|
2.98204
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.92309
|
|
POLR2K
|
polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
|
2.79646
|
|
GPATCH8
|
G patch domain containing 8
|
2.54973
|
|
PMM2
|
phosphomannomutase 2
|
2.41786
|
|
AASS
|
aminoadipate-semialdehyde synthase
|
2.394
|
|
ANKRD46
|
ankyrin repeat domain 46
|
2.38939
|
|
HEBP1
|
heme binding protein 1
|
2.3049
|
|
RPRD2
|
regulation of nuclear pre-mRNA domain containing 2
|
2.29746
|
|
ZNF589
|
zinc finger protein 589
|
2.25389
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.18809
|
|
FAAP100
|
FA core complex associated protein 100
|
2.16514
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.0945
|
|
MPHOSPH10
|
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
|
2.08723
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.06468
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.04571
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-8.01125
|
|
ADI1
|
acireductone dioxygenase 1
|
-6.57463
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-6.34179
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-5.25028
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-4.95655
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.63091
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-4.55498
|
|
MAP7
|
microtubule-associated protein 7
|
-4.32612
|
|
ZW10
|
zw10 kinetochore protein
|
-3.98232
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.79642
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.76777
|
|
RPIA
|
ribose 5-phosphate isomerase A
|
-3.43808
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.96107
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.84177
|
|
TSPAN4
|
tetraspanin 4
|
-2.81563
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.69081
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.52326
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-2.46233
|
|
EGF
|
epidermal growth factor
|
-2.44779
|
|
PSMB10
|
proteasome (prosome, macropain) subunit, beta type, 10
|
-2.35851
|
|
DPM1
|
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
|
-2.31025
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.24782
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.24167
|
|
DNM1L
|
dynamin 1-like
|
-2.20236
|
|
CPNE3
|
copine III
|
-2.1819
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.09783
|
|
USP6NL
|
USP6 N-terminal like
|
-2.06461
|
