| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1-amino-2,4-dibromoanthraquinone 25.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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60 genes differentially expressed following the CRCGN012_HEPG2_24H:O19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 5.86787 |
| CCL2 | chemokine (C-C motif) ligand 2 | 5.77959 |
| NOTCH1 | notch 1 | 3.98929 |
| BZW2 | basic leucine zipper and W2 domains 2 | 3.88582 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.7265 |
| STIMATE | STIM activating enhancer | 3.65711 |
| UBQLN2 | ubiquilin 2 | 3.36013 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.25642 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | 3.16158 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.0689 |
| LCN2 | lipocalin 2 | 3.06524 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 2.99092 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.93046 |
| ABHD6 | abhydrolase domain containing 6 | 2.84212 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.8103 |
| TXNRD1 | thioredoxin reductase 1 | 2.80078 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 2.68913 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.56724 |
| COPS7A | COP9 signalosome subunit 7A | 2.51631 |
| VGLL4 | vestigial-like family member 4 | 2.47752 |
| RAB21 | RAB21, member RAS oncogene family | 2.41057 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.39083 |
| TEX10 | testis expressed 10 | 2.38001 |
| CSK | c-src tyrosine kinase | 2.35686 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.26888 |
| CHN1 | chimerin 1 | 2.2654 |
| PFKL | phosphofructokinase, liver | 2.26536 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.23258 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | 2.16839 |
| EPN2 | epsin 2 | 2.09156 |
| SLC25A46 | solute carrier family 25, member 46 | 2.04609 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF586 | zinc finger protein 586 | -5.96645 |
| CCNB2 | cyclin B2 | -5.42932 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.27861 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.78542 |
| CCDC86 | coiled-coil domain containing 86 | -3.38398 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.29314 |
| TRIB3 | tribbles pseudokinase 3 | -3.22406 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.12915 |
| LDHD | lactate dehydrogenase D | -3.0528 |
| CAB39 | calcium binding protein 39 | -3.02281 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.94436 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.906 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.86573 |
| NGRN | neugrin, neurite outgrowth associated | -2.7982 |
| MRPS2 | mitochondrial ribosomal protein S2 | -2.58423 |
| PEG10 | paternally expressed 10 | -2.56194 |
| GDF15 | growth differentiation factor 15 | -2.55557 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.52696 |
| RPIA | ribose 5-phosphate isomerase A | -2.51612 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.49053 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -2.4534 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.4223 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.30647 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -2.2226 |
| CDC25B | cell division cycle 25B | -2.21969 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.19547 |
| SLC35F2 | solute carrier family 35, member F2 | -2.1903 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.03536 |
| UGDH | UDP-glucose 6-dehydrogenase | -2.03101 |
