CRCGN012_HEPG2_24H:O21 Gene Set
Genes
54 genes differentially expressed following the CRCGN012_HEPG2_24H:O21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STIMATE
|
STIM activating enhancer
|
5.04295
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.89223
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.88935
|
|
SQOR
|
sulfide quinone oxidoreductase
|
4.64251
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
4.25012
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.84971
|
|
TRIM13
|
tripartite motif containing 13
|
3.57553
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
3.46255
|
|
PFKL
|
phosphofructokinase, liver
|
3.30469
|
|
CCNF
|
cyclin F
|
3.23554
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
3.19889
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
3.17212
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
3.053
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
3.02575
|
|
VGLL4
|
vestigial-like family member 4
|
2.85488
|
|
CTSL
|
cathepsin L
|
2.7644
|
|
KIF5C
|
kinesin family member 5C
|
2.70938
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.65659
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.54202
|
|
KLHL9
|
kelch-like family member 9
|
2.43118
|
|
MEST
|
mesoderm specific transcript
|
2.37623
|
|
CREG1
|
cellular repressor of E1A-stimulated genes 1
|
2.36838
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.29178
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.2721
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
2.16768
|
|
SHC1
|
SHC (Src homology 2 domain containing) transforming protein 1
|
2.12279
|
|
TEX10
|
testis expressed 10
|
2.00315
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-6.33176
|
|
LDHD
|
lactate dehydrogenase D
|
-5.22153
|
|
ADI1
|
acireductone dioxygenase 1
|
-5.06579
|
|
DNM1L
|
dynamin 1-like
|
-4.87084
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.77266
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.6654
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.60418
|
|
CDC20
|
cell division cycle 20
|
-4.49361
|
|
MAP7
|
microtubule-associated protein 7
|
-4.04117
|
|
GNAS
|
GNAS complex locus
|
-3.83627
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.68064
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.56376
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.54835
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-3.33617
|
|
CCNB2
|
cyclin B2
|
-3.33332
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-3.08884
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-3.06927
|
|
ZW10
|
zw10 kinetochore protein
|
-2.79785
|
|
WASHC4
|
WASH complex subunit 4
|
-2.67952
|
|
MYL9
|
myosin, light chain 9, regulatory
|
-2.56869
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.53702
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
-2.39223
|
|
GDF15
|
growth differentiation factor 15
|
-2.30548
|
|
FBLN5
|
fibulin 5
|
-2.27224
|
|
TTPAL
|
tocopherol (alpha) transfer protein-like
|
-2.23112
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.11291
|
|
TESPA1
|
thymocyte expressed, positive selection associated 1
|
-2.00976
|
