| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1-amino-2,4-dibromoanthraquinone 3.13 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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58 genes differentially expressed following the CRCGN012_HEPG2_24H:O22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.78255 |
| LCN2 | lipocalin 2 | 4.66379 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.46561 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.43181 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.23689 |
| NOTCH1 | notch 1 | 4.03531 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 3.87108 |
| EPN2 | epsin 2 | 3.68874 |
| UBQLN2 | ubiquilin 2 | 3.64633 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.13459 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 3.12596 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 3.04418 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.92869 |
| KIF5C | kinesin family member 5C | 2.61731 |
| MAP7 | microtubule-associated protein 7 | 2.59476 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.55296 |
| CYCS | cytochrome c, somatic | 2.45224 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.39873 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.33571 |
| SLIRP | SRA stem-loop interacting RNA binding protein | 2.28455 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.23516 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | 2.22965 |
| EPHA3 | EPH receptor A3 | 2.20887 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 2.18456 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 2.13327 |
| TEX10 | testis expressed 10 | 2.03191 |
| PLAUR | plasminogen activator, urokinase receptor | 2.02648 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NT5DC2 | 5'-nucleotidase domain containing 2 | -8.71482 |
| TRIB3 | tribbles pseudokinase 3 | -8.63366 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -8.5722 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -8.56819 |
| PLK1 | polo-like kinase 1 | -5.57818 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -4.89384 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -4.44665 |
| THAP11 | THAP domain containing 11 | -4.28114 |
| CCNB1 | cyclin B1 | -4.15967 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -4.01549 |
| VAT1 | vesicle amine transport 1 | -3.97658 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.8517 |
| RBM15B | RNA binding motif protein 15B | -3.72624 |
| GTPBP8 | GTP-binding protein 8 (putative) | -3.44823 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.38153 |
| PEG10 | paternally expressed 10 | -3.34447 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.28629 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.68717 |
| PCNA | proliferating cell nuclear antigen | -2.57859 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -2.50963 |
| SMNDC1 | survival motor neuron domain containing 1 | -2.41664 |
| USP6NL | USP6 N-terminal like | -2.36384 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.33412 |
| SEPHS2 | selenophosphate synthetase 2 | -2.23142 |
| RASA2 | RAS p21 protein activator 2 | -2.21303 |
| KLHDC3 | kelch domain containing 3 | -2.20977 |
| EGF | epidermal growth factor | -2.0935 |
| MYL9 | myosin, light chain 9, regulatory | -2.04048 |
| TMEM186 | transmembrane protein 186 | -2.02353 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) | -2.01836 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -2.01832 |
