| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1-amino-2,4-dibromoanthraquinone 0.78 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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59 genes differentially expressed following the CRCGN012_HEPG2_24H:O24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ATP11B | ATPase, class VI, type 11B | 5.06466 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.75327 |
| ADRB2 | adrenoceptor beta 2, surface | 4.70043 |
| CSK | c-src tyrosine kinase | 4.56874 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.70687 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.28138 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 3.23346 |
| E2F2 | E2F transcription factor 2 | 3.02653 |
| HEBP1 | heme binding protein 1 | 3.01447 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 2.89704 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 2.70762 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.68715 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.6108 |
| CDK6 | cyclin-dependent kinase 6 | 2.43731 |
| CHMP6 | charged multivesicular body protein 6 | 2.43459 |
| MICALL1 | MICAL-like 1 | 2.3443 |
| CTSV | cathepsin V | 2.33327 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 2.31396 |
| UBQLN2 | ubiquilin 2 | 2.26287 |
| TBXA2R | thromboxane A2 receptor | 2.23172 |
| ZNF747 | zinc finger protein 747 | 2.1814 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | 2.16635 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 2.13323 |
| ETFA | electron-transfer-flavoprotein, alpha polypeptide | 2.07702 |
| EPHA3 | EPH receptor A3 | 2.04791 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 2.03939 |
| EDN1 | endothelin 1 | 2.01467 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GDF15 | growth differentiation factor 15 | -5.48129 |
| COG7 | component of oligomeric golgi complex 7 | -5.16832 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.93991 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -4.931 |
| LDHD | lactate dehydrogenase D | -4.7958 |
| ADI1 | acireductone dioxygenase 1 | -4.20422 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.4063 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -3.38372 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | -2.98689 |
| TBCB | tubulin folding cofactor B | -2.8477 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.7568 |
| GPATCH1 | G patch domain containing 1 | -2.74063 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.72508 |
| COPG1 | coatomer protein complex, subunit gamma 1 | -2.64507 |
| CAPNS1 | calpain, small subunit 1 | -2.60378 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -2.59816 |
| NDUFA3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa | -2.50996 |
| TMEM147 | transmembrane protein 147 | -2.43457 |
| RBM42 | RNA binding motif protein 42 | -2.40004 |
| NPIPA6 | nuclear pore complex interacting protein family, member A6 | -2.3659 |
| PSMD8 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | -2.34905 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | -2.31515 |
| LIN37 | lin-37 DREAM MuvB core complex component | -2.31145 |
| SERTAD3 | SERTA domain containing 3 | -2.24464 |
| RBBP5 | retinoblastoma binding protein 5 | -2.14355 |
| VAT1 | vesicle amine transport 1 | -2.14088 |
| EGF | epidermal growth factor | -2.13244 |
| ZNF146 | zinc finger protein 146 | -2.12444 |
| BIRC2 | baculoviral IAP repeat containing 2 | -2.09468 |
| MMP7 | matrix metallopeptidase 7 | -2.0722 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | -2.05534 |
| XPO7 | exportin 7 | -2.01334 |
