| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 3,3',5,5'-tetrabromobisphenol a 20.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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82 genes differentially expressed following the CRCGN012_HEPG2_24H:P02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BACE2 | beta-site APP-cleaving enzyme 2 | 7.22491 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 5.01454 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 4.72186 |
| RPL39L | ribosomal protein L39-like | 4.22911 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 4.17367 |
| CHMP6 | charged multivesicular body protein 6 | 4.12937 |
| MOK | MOK protein kinase | 3.98553 |
| CSK | c-src tyrosine kinase | 3.9838 |
| EPHB2 | EPH receptor B2 | 3.96845 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 3.79221 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.6899 |
| PRKCH | protein kinase C, eta | 3.68925 |
| JADE2 | jade family PHD finger 2 | 3.55057 |
| ABHD6 | abhydrolase domain containing 6 | 3.43972 |
| DIPK1A | divergent protein kinase domain 1A | 3.08197 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.99629 |
| GRWD1 | glutamate-rich WD repeat containing 1 | 2.94849 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.90584 |
| GATA3 | GATA binding protein 3 | 2.89591 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | 2.77217 |
| GPATCH8 | G patch domain containing 8 | 2.73123 |
| NOSIP | nitric oxide synthase interacting protein | 2.65957 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 2.59574 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.57567 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.54243 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.49447 |
| POU4F1 | POU class 4 homeobox 1 | 2.463 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | 2.34645 |
| TERT | telomerase reverse transcriptase | 2.29638 |
| MAMLD1 | mastermind-like domain containing 1 | 2.29521 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.2782 |
| LRP10 | low density lipoprotein receptor-related protein 10 | 2.26087 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 2.23319 |
| SHPK | sedoheptulokinase | 2.20226 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.17735 |
| CYCS | cytochrome c, somatic | 2.14924 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.13746 |
| BFSP2 | beaded filament structural protein 2, phakinin | 2.11868 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | 2.10771 |
| PIWIL2 | piwi-like RNA-mediated gene silencing 2 | 2.09719 |
| LOC122526780 | uncharacterized LOC122526780 | 2.08922 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 2.08815 |
| ICAM1 | intercellular adhesion molecule 1 | 2.04057 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -7.4235 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -7.29818 |
| NUP93 | nucleoporin 93kDa | -5.9338 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.17893 |
| GDF15 | growth differentiation factor 15 | -5.0 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -4.67387 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -4.29742 |
| NGRN | neugrin, neurite outgrowth associated | -4.19856 |
| CCDC86 | coiled-coil domain containing 86 | -4.0678 |
| SLC35F2 | solute carrier family 35, member F2 | -3.89301 |
| CDC20 | cell division cycle 20 | -3.68293 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -3.67416 |
| CAB39 | calcium binding protein 39 | -3.54846 |
| ENOPH1 | enolase-phosphatase 1 | -3.44574 |
| GOLT1B | golgi transport 1B | -3.37112 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -3.20296 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.86796 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.77839 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.76132 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.6913 |
| SCAND1 | SCAN domain containing 1 | -2.66893 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -2.65601 |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 | -2.64246 |
| VAT1 | vesicle amine transport 1 | -2.64152 |
| ZW10 | zw10 kinetochore protein | -2.49349 |
| ICAM3 | intercellular adhesion molecule 3 | -2.45228 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -2.45098 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -2.43097 |
| DECR1 | 2,4-dienoyl CoA reductase 1, mitochondrial | -2.38335 |
| WASHC4 | WASH complex subunit 4 | -2.29991 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.23726 |
| DYNLRB1 | dynein, light chain, roadblock-type 1 | -2.21469 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.2138 |
| MSN | moesin | -2.17814 |
| LSM8 | LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.12401 |
| EGF | epidermal growth factor | -2.08462 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.05225 |
| CDC25B | cell division cycle 25B | -2.03786 |
| HMG20B | high mobility group 20B | -2.01422 |
