CRCGN012_HEPG2_24H:P05 Gene Set
Genes
55 genes differentially expressed following the CRCGN012_HEPG2_24H:P05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
10.0
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
6.04682
|
|
MOK
|
MOK protein kinase
|
5.2753
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
5.1092
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
5.05315
|
|
MYLK
|
myosin light chain kinase
|
4.97425
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
4.81485
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.5887
|
|
CCNA1
|
cyclin A1
|
4.2431
|
|
CSK
|
c-src tyrosine kinase
|
4.2385
|
|
FZD7
|
frizzled class receptor 7
|
3.82323
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.7004
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.5348
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.40753
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.22057
|
|
JADE2
|
jade family PHD finger 2
|
2.97455
|
|
EVL
|
Enah/Vasp-like
|
2.9266
|
|
TEX10
|
testis expressed 10
|
2.68595
|
|
PCNA
|
proliferating cell nuclear antigen
|
2.65685
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.6168
|
|
KIF14
|
kinesin family member 14
|
2.4454
|
|
FASTK
|
Fas-activated serine/threonine kinase
|
2.0575
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.0436
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC25B
|
cell division cycle 25B
|
-6.02735
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-5.6251
|
|
TRIB3
|
tribbles pseudokinase 3
|
-5.227
|
|
ISOC1
|
isochorismatase domain containing 1
|
-5.143
|
|
DUSP6
|
dual specificity phosphatase 6
|
-4.2894
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.97102
|
|
GDF15
|
growth differentiation factor 15
|
-3.964
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.9235
|
|
WASHC4
|
WASH complex subunit 4
|
-3.9056
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-3.4678
|
|
CD320
|
CD320 molecule
|
-3.32145
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-3.17025
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-3.1016
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.98082
|
|
EGF
|
epidermal growth factor
|
-2.62515
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.5044
|
|
AP3S1
|
adaptor-related protein complex 3, sigma 1 subunit
|
-2.4787
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.46345
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.40665
|
|
CYRIA
|
CYFIP related Rac1 interactor A
|
-2.2971
|
|
SETBP1
|
SET binding protein 1
|
-2.2662
|
|
BSPRY
|
B-box and SPRY domain containing
|
-2.25015
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.23105
|
|
APOD
|
apolipoprotein D
|
-2.20675
|
|
ADAMTS5
|
ADAM metallopeptidase with thrombospondin type 1 motif, 5
|
-2.1884
|
|
SLC49A3
|
solute carrier family 49 member 3
|
-2.1806
|
|
SYNGAP1
|
synaptic Ras GTPase activating protein 1
|
-2.14235
|
|
CLTB
|
clathrin, light chain B
|
-2.12343
|
|
OMD
|
osteomodulin
|
-2.10105
|
|
TES
|
testin LIM domain protein
|
-2.08742
|
|
OLFML1
|
olfactomedin-like 1
|
-2.04665
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.03763
|
