| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-(1-naphthyl)ethylenediamine.2hcl 10.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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58 genes differentially expressed following the CRCGN012_HEPG2_24H:P09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 6.86477 |
| UBQLN2 | ubiquilin 2 | 6.85202 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.62956 |
| PRR15L | proline rich 15-like | 5.32689 |
| VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 4.69099 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.48987 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 3.44164 |
| CHMP6 | charged multivesicular body protein 6 | 3.30811 |
| ATP11B | ATPase, class VI, type 11B | 3.29447 |
| NOTCH1 | notch 1 | 3.2614 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 3.13862 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 3.12608 |
| MSRA | methionine sulfoxide reductase A | 2.92482 |
| STIMATE | STIM activating enhancer | 2.7799 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.76781 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.72346 |
| DIPK1A | divergent protein kinase domain 1A | 2.7108 |
| FZD7 | frizzled class receptor 7 | 2.64349 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.59409 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.42169 |
| EPHA3 | EPH receptor A3 | 2.38888 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.3866 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.38147 |
| ALDOC | aldolase C, fructose-bisphosphate | 2.37917 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.26827 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | 2.25573 |
| PLK2 | polo-like kinase 2 | 2.24393 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.22569 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 2.13289 |
| EIF4EBP3 | eukaryotic translation initiation factor 4E binding protein 3 | 2.05203 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.04995 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF586 | zinc finger protein 586 | -6.96071 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.85604 |
| CCNB2 | cyclin B2 | -5.61785 |
| GTPBP8 | GTP-binding protein 8 (putative) | -3.79681 |
| DUSP6 | dual specificity phosphatase 6 | -3.74897 |
| YME1L1 | YME1-like 1 ATPase | -3.38935 |
| MAP7 | microtubule-associated protein 7 | -3.17933 |
| IER3 | immediate early response 3 | -3.12309 |
| PLK1 | polo-like kinase 1 | -2.9857 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.90917 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -2.89255 |
| VAT1 | vesicle amine transport 1 | -2.89085 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.81312 |
| NGRN | neugrin, neurite outgrowth associated | -2.77817 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -2.75931 |
| ZNF134 | zinc finger protein 134 | -2.72137 |
| TLCD3A | TLC domain containing 3A | -2.70905 |
| UGDH | UDP-glucose 6-dehydrogenase | -2.47225 |
| RBM15B | RNA binding motif protein 15B | -2.40793 |
| USP6NL | USP6 N-terminal like | -2.30178 |
| GNAS | GNAS complex locus | -2.19739 |
| ZNF551 | zinc finger protein 551 | -2.18375 |
| SIRPG | signal-regulatory protein gamma | -2.17983 |
| ZNF304 | zinc finger protein 304 | -2.14147 |
| ZNF587B | zinc finger protein 587B | -2.11636 |
| ZW10 | zw10 kinetochore protein | -2.06929 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.05858 |
