CRCGN012_HEPG2_24H:P10 Gene Set
Genes
47 genes differentially expressed following the CRCGN012_HEPG2_24H:P10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
6.39257
|
|
CSK
|
c-src tyrosine kinase
|
6.31168
|
|
CHN1
|
chimerin 1
|
5.72044
|
|
CYCS
|
cytochrome c, somatic
|
4.31197
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.98321
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
3.98307
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.89461
|
|
DHX29
|
DEAH (Asp-Glu-Ala-His) box polypeptide 29
|
3.87879
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
3.33327
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.3123
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.19121
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.78397
|
|
GATA3
|
GATA binding protein 3
|
2.72609
|
|
HDGFL3
|
HDGF like 3
|
2.70317
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.41703
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.31018
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.25401
|
|
CBR3
|
carbonyl reductase 3
|
2.17305
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MAPK13
|
mitogen-activated protein kinase 13
|
-5.2826
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.73579
|
|
CDC20
|
cell division cycle 20
|
-3.66242
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.51126
|
|
DSG2
|
desmoglein 2
|
-3.50589
|
|
VAT1
|
vesicle amine transport 1
|
-3.50548
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.48793
|
|
GOLT1B
|
golgi transport 1B
|
-3.4851
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.36135
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.29555
|
|
ZNF586
|
zinc finger protein 586
|
-3.23581
|
|
RNF167
|
ring finger protein 167
|
-2.93864
|
|
LDHD
|
lactate dehydrogenase D
|
-2.92837
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.92647
|
|
GNAS
|
GNAS complex locus
|
-2.81222
|
|
COG2
|
component of oligomeric golgi complex 2
|
-2.80226
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.63451
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-2.63414
|
|
EGF
|
epidermal growth factor
|
-2.61128
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.57037
|
|
PSRC1
|
proline/serine-rich coiled-coil 1
|
-2.30559
|
|
PEG10
|
paternally expressed 10
|
-2.23531
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.13269
|
|
CCNB2
|
cyclin B2
|
-2.12422
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.08843
|
|
WASHC4
|
WASH complex subunit 4
|
-2.07507
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.0507
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.03612
|
|
VWA1
|
von Willebrand factor A domain containing 1
|
-2.03329
|
