CRCGN012_HEPG2_24H:P11 Gene Set
Genes
40 genes differentially expressed following the CRCGN012_HEPG2_24H:P11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
6.73055
|
|
ABHD6
|
abhydrolase domain containing 6
|
6.20263
|
|
ATP11B
|
ATPase, class VI, type 11B
|
4.00571
|
|
ZNF589
|
zinc finger protein 589
|
3.81151
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.55966
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.54315
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.49984
|
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
3.25577
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
3.08883
|
|
E2F2
|
E2F transcription factor 2
|
2.83157
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
2.75145
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.63761
|
|
TBXA2R
|
thromboxane A2 receptor
|
2.62553
|
|
CCNH
|
cyclin H
|
2.50225
|
|
MBOAT7
|
membrane bound O-acyltransferase domain containing 7
|
2.38896
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.37478
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.27056
|
|
JADE2
|
jade family PHD finger 2
|
2.03034
|
|
MEST
|
mesoderm specific transcript
|
2.01519
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-6.46538
|
|
CCNB2
|
cyclin B2
|
-4.28737
|
|
RPS5
|
ribosomal protein S5
|
-3.99362
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.91697
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.63308
|
|
LDHD
|
lactate dehydrogenase D
|
-3.3239
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-3.13789
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.91681
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.82548
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.57681
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.49775
|
|
MVP
|
major vault protein
|
-2.4856
|
|
CDC25B
|
cell division cycle 25B
|
-2.47069
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.45328
|
|
USP6NL
|
USP6 N-terminal like
|
-2.34432
|
|
TOR1A
|
torsin family 1, member A (torsin A)
|
-2.23419
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
-2.16095
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.07039
|
|
ORMDL2
|
ORMDL sphingolipid biosynthesis regulator 2
|
-2.03458
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.01347
|
|
PDLIM1
|
PDZ and LIM domain 1
|
-2.00205
|
