| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | n-(1-naphthyl)ethylenediamine.2hcl 1.25 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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49 genes differentially expressed following the CRCGN012_HEPG2_24H:P12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 6.74723 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 6.46566 |
| E2F2 | E2F transcription factor 2 | 6.37169 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 6.26764 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 5.85314 |
| GPER1 | G protein-coupled estrogen receptor 1 | 5.04698 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.01491 |
| TBPL1 | TBP-like 1 | 3.83471 |
| CSK | c-src tyrosine kinase | 3.77341 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.46131 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.33214 |
| CHMP6 | charged multivesicular body protein 6 | 3.31349 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.25321 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 2.91574 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.87169 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.83442 |
| NOTCH1 | notch 1 | 2.82838 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.53126 |
| HEBP1 | heme binding protein 1 | 2.51359 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.40452 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 | 2.39167 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.35105 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 2.28666 |
| NMU | neuromedin U | 2.25841 |
| DIPK1A | divergent protein kinase domain 1A | 2.21127 |
| RALGDS | ral guanine nucleotide dissociation stimulator | 2.17071 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.04588 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -7.25577 |
| LDHD | lactate dehydrogenase D | -7.1115 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -4.2357 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.77536 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.63101 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.57358 |
| CLTB | clathrin, light chain B | -3.51611 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.12467 |
| MAP7 | microtubule-associated protein 7 | -3.00826 |
| ADI1 | acireductone dioxygenase 1 | -2.89812 |
| PRPF4 | pre-mRNA processing factor 4 | -2.70663 |
| VDAC1 | voltage-dependent anion channel 1 | -2.68579 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.59714 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.56822 |
| RPL18A | ribosomal protein L18a | -2.36524 |
| SSBP2 | single-stranded DNA binding protein 2 | -2.29931 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -2.26573 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -2.22243 |
| CCNB1 | cyclin B1 | -2.14188 |
| HMG20B | high mobility group 20B | -2.12807 |
| TRIM9 | tripartite motif containing 9 | -2.03371 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.0202 |
