CRCGN012_HEPG2_24H:P13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description erythrosine 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

54 genes differentially expressed following the CRCGN012_HEPG2_24H:P13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CBR3 carbonyl reductase 3 6.28769
CHN1 chimerin 1 5.55789
STIMATE STIM activating enhancer 5.14892
STK10 serine/threonine kinase 10 5.10925
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.90505
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 4.79337
TIAM1 T-cell lymphoma invasion and metastasis 1 4.75536
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 4.69116
ABHD4 abhydrolase domain containing 4 4.6182
PPARG peroxisome proliferator-activated receptor gamma 4.42945
CXCL2 chemokine (C-X-C motif) ligand 2 4.37874
MELK maternal embryonic leucine zipper kinase 4.35203
PEX11A peroxisomal biogenesis factor 11 alpha 3.67851
GPER1 G protein-coupled estrogen receptor 1 3.52744
SFTPB surfactant protein B 3.27514
MOK MOK protein kinase 2.84867
CIAO3 cytosolic iron-sulfur assembly component 3 2.83227
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.69692
GPATCH8 G patch domain containing 8 2.57909
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.54274
TEX10 testis expressed 10 2.48571
ZNF589 zinc finger protein 589 2.46605
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 2.41279
CSK c-src tyrosine kinase 2.40844
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.33749
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 2.33529
EVL Enah/Vasp-like 2.08087
FOXF1 forkhead box F1 2.06728

decreased expression

Symbol Name Standardized Value
GTPBP8 GTP-binding protein 8 (putative) -5.32024
DNM1L dynamin 1-like -5.31012
WASHC4 WASH complex subunit 4 -4.70939
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.67304
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.59804
CCNB2 cyclin B2 -4.54953
ADI1 acireductone dioxygenase 1 -4.5038
ITFG1 integrin alpha FG-GAP repeat containing 1 -4.46477
UBE3C ubiquitin protein ligase E3C -3.30835
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -3.21045
CDC20 cell division cycle 20 -2.81945
RPS4Y1 ribosomal protein S4, Y-linked 1 -2.6757
IFRD2 interferon-related developmental regulator 2 -2.62043
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.50213
ZMIZ1 zinc finger, MIZ-type containing 1 -2.41534
DDIT4 DNA-damage-inducible transcript 4 -2.40786
EGF epidermal growth factor -2.37379
RGS2 regulator of G-protein signaling 2 -2.19007
EFNA1 ephrin-A1 -2.14877
MYL9 myosin, light chain 9, regulatory -2.12094
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) -2.10973
LDHD lactate dehydrogenase D -2.1021
MRPL42 mitochondrial ribosomal protein L42 -2.0971
USP1 ubiquitin specific peptidase 1 -2.0934
MAPK13 mitogen-activated protein kinase 13 -2.01433
PCNA proliferating cell nuclear antigen -2.01046