| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | erythrosine 20.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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96 genes differentially expressed following the CRCGN012_HEPG2_24H:P14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 6.19417 |
| CHMP6 | charged multivesicular body protein 6 | 5.26279 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 5.10203 |
| PNKP | polynucleotide kinase 3'-phosphatase | 4.87741 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 4.79675 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.68719 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.67381 |
| DENND2D | DENN/MADD domain containing 2D | 4.64208 |
| PMM2 | phosphomannomutase 2 | 4.60455 |
| LOC122526780 | uncharacterized LOC122526780 | 4.5337 |
| MEF2C | myocyte enhancer factor 2C | 4.31669 |
| EPN2 | epsin 2 | 3.99402 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 3.87309 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.71704 |
| ABHD6 | abhydrolase domain containing 6 | 3.66936 |
| CCNF | cyclin F | 3.59568 |
| HYOU1 | hypoxia up-regulated 1 | 3.39642 |
| SLC75A1 | solute carrier family 75 member 1 | 3.07553 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.00569 |
| RPL39L | ribosomal protein L39-like | 2.77019 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.66764 |
| EVL | Enah/Vasp-like | 2.58779 |
| CD63 | CD63 molecule | 2.44576 |
| RAB21 | RAB21, member RAS oncogene family | 2.40266 |
| LSR | lipolysis stimulated lipoprotein receptor | 2.36914 |
| TXNL4B | thioredoxin-like 4B | 2.29365 |
| SETD5 | SET domain containing 5 | 2.27227 |
| STK10 | serine/threonine kinase 10 | 2.26695 |
| AACS | acetoacetyl-CoA synthetase | 2.25013 |
| DOCK1 | dedicator of cytokinesis 1 | 2.24472 |
| RASL10A | RAS-like, family 10, member A | 2.23839 |
| HTRA1 | HtrA serine peptidase 1 | 2.2268 |
| KCNIP1 | Kv channel interacting protein 1 | 2.21944 |
| NID1 | nidogen 1 | 2.19068 |
| ZMYM2 | zinc finger, MYM-type 2 | 2.17992 |
| ATP11B | ATPase, class VI, type 11B | 2.17596 |
| ECD | ecdysoneless homolog (Drosophila) | 2.14821 |
| TRIM8 | tripartite motif containing 8 | 2.13303 |
| ADRB2 | adrenoceptor beta 2, surface | 2.12868 |
| TBPL1 | TBP-like 1 | 2.11706 |
| NRN1 | neuritin 1 | 2.10329 |
| SFXN3 | sideroflexin 3 | 2.09881 |
| SATB1 | SATB homeobox 1 | 2.08773 |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 | 2.08399 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 2.06125 |
| LZTR1 | leucine-zipper-like transcription regulator 1 | 2.04504 |
| NPTX2 | neuronal pentraxin II | 2.038 |
| SLC8A2 | solute carrier family 8 (sodium/calcium exchanger), member 2 | 2.01007 |
| TBC1D17 | TBC1 domain family, member 17 | 2.00783 |
| SYN2 | synapsin II | 2.00626 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR4 | fibroblast growth factor receptor 4 | -6.1901 |
| LDHD | lactate dehydrogenase D | -4.95157 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.83193 |
| IFRD2 | interferon-related developmental regulator 2 | -4.3237 |
| VAT1 | vesicle amine transport 1 | -3.72885 |
| CHMP4B | charged multivesicular body protein 4B | -3.7064 |
| PCNA | proliferating cell nuclear antigen | -3.68939 |
| CDC20 | cell division cycle 20 | -3.61701 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -3.59272 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.52215 |
| CCNB2 | cyclin B2 | -3.46883 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -3.37936 |
| YME1L1 | YME1-like 1 ATPase | -3.31892 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.2951 |
| ZNF586 | zinc finger protein 586 | -3.23404 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.2323 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.22352 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -3.18384 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -3.10915 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.94205 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.91871 |
| VDAC1 | voltage-dependent anion channel 1 | -2.78362 |
| SFMBT1 | Scm-like with four mbt domains 1 | -2.69462 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -2.67673 |
| MRPS2 | mitochondrial ribosomal protein S2 | -2.64067 |
| SLC35F2 | solute carrier family 35, member F2 | -2.55456 |
| PRPF4 | pre-mRNA processing factor 4 | -2.5453 |
| CDC25B | cell division cycle 25B | -2.43654 |
| C5 | complement component 5 | -2.40389 |
| TMEM38B | transmembrane protein 38B | -2.38495 |
| SLC25A13 | solute carrier family 25 (aspartate/glutamate carrier), member 13 | -2.37088 |
| GDF15 | growth differentiation factor 15 | -2.34067 |
| S100A9 | S100 calcium binding protein A9 | -2.27588 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) | -2.26876 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -2.26783 |
| REEP5 | receptor accessory protein 5 | -2.26545 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.23095 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.23068 |
| NAT10 | N-acetyltransferase 10 (GCN5-related) | -2.14342 |
| NFIL3 | nuclear factor, interleukin 3 regulated | -2.12739 |
| SCGN | secretagogin, EF-hand calcium binding protein | -2.11539 |
| AP1M2 | adaptor-related protein complex 1, mu 2 subunit | -2.08364 |
| STK38 | serine/threonine kinase 38 | -2.06475 |
| MAP7 | microtubule-associated protein 7 | -2.0627 |
| NEFH | neurofilament, heavy polypeptide | -2.04961 |
| PDHX | pyruvate dehydrogenase complex, component X | -2.03406 |
