CRCGN012_HEPG2_24H:P15 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description erythrosine 10.0 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

41 genes differentially expressed following the CRCGN012_HEPG2_24H:P15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
LOC122526780 uncharacterized LOC122526780 5.3889
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 4.46131
NOSIP nitric oxide synthase interacting protein 4.28219
GSTZ1 glutathione S-transferase zeta 1 3.62307
DYNLT3 dynein, light chain, Tctex-type 3 3.05011
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 2.75409
CYCS cytochrome c, somatic 2.70822
GPATCH8 G patch domain containing 8 2.70236
TIAM1 T-cell lymphoma invasion and metastasis 1 2.67876
ADRB2 adrenoceptor beta 2, surface 2.67354
CDK6 cyclin-dependent kinase 6 2.59147
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.56443
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 2.55864
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform 2.55427
NR1H2 nuclear receptor subfamily 1, group H, member 2 2.49964
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.48567
MYLK myosin light chain kinase 2.44385
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 2.41612
H2BC12 H2B clustered histone 12 2.38691
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 2.22569
ARID4B AT rich interactive domain 4B (RBP1-like) 2.18117
HSPA1A heat shock 70kDa protein 1A 2.13169
TMEM184C transmembrane protein 184C 2.03267

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -7.63471
ZNF586 zinc finger protein 586 -4.81096
KDM3A lysine (K)-specific demethylase 3A -4.73702
CD320 CD320 molecule -4.18909
DERA deoxyribose-phosphate aldolase (putative) -3.53321
DNM1L dynamin 1-like -3.24909
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -3.20082
ZMIZ1 zinc finger, MIZ-type containing 1 -3.00955
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.97778
RPS5 ribosomal protein S5 -2.85907
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.85699
TRIB3 tribbles pseudokinase 3 -2.75969
SNX11 sorting nexin 11 -2.54166
TWF2 twinfilin actin binding protein 2 -2.3114
BARX2 BARX homeobox 2 -2.17893
NGRN neugrin, neurite outgrowth associated -2.16381
CGREF1 cell growth regulator with EF-hand domain 1 -2.08672
VNN2 vanin 2 -2.00694