CRCGN012_HEPG2_24H:P17 Gene Set
Genes
46 genes differentially expressed following the CRCGN012_HEPG2_24H:P17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
10.0
|
|
CYCS
|
cytochrome c, somatic
|
4.12422
|
|
CHN1
|
chimerin 1
|
4.06504
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.60136
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.57983
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.26413
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.25468
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.19471
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.12104
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
3.08311
|
|
MYLK
|
myosin light chain kinase
|
3.05391
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.91765
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
2.74313
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.74216
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.6529
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
2.64407
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.35544
|
|
E2F2
|
E2F transcription factor 2
|
2.35388
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.34224
|
|
IDE
|
insulin-degrading enzyme
|
2.23641
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.22363
|
|
GATA3
|
GATA binding protein 3
|
2.20723
|
|
NEO1
|
neogenin 1
|
2.18512
|
|
PIGB
|
phosphatidylinositol glycan anchor biosynthesis, class B
|
2.17014
|
|
PTK2
|
protein tyrosine kinase 2
|
2.12308
|
|
IL1B
|
interleukin 1, beta
|
2.11582
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.49524
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-6.48694
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-5.65229
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-5.50086
|
|
PLK1
|
polo-like kinase 1
|
-3.86204
|
|
VAT1
|
vesicle amine transport 1
|
-3.56164
|
|
MTA1
|
metastasis associated 1
|
-3.44269
|
|
SNX11
|
sorting nexin 11
|
-3.40906
|
|
WASHC4
|
WASH complex subunit 4
|
-2.99662
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.99277
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.96555
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.94014
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.71624
|
|
CD320
|
CD320 molecule
|
-2.68523
|
|
RNF167
|
ring finger protein 167
|
-2.59447
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.45736
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.28098
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
-2.19829
|
|
EGF
|
epidermal growth factor
|
-2.19758
|
|
BCKDK
|
branched chain ketoacid dehydrogenase kinase
|
-2.09048
|
