CRCGN012_HEPG2_24H:P18 Gene Set
Genes
39 genes differentially expressed following the CRCGN012_HEPG2_24H:P18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.27762
|
|
RPL39L
|
ribosomal protein L39-like
|
5.6875
|
|
CSK
|
c-src tyrosine kinase
|
5.62859
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
4.70946
|
|
PRR15L
|
proline rich 15-like
|
3.63121
|
|
STK10
|
serine/threonine kinase 10
|
3.54972
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.29586
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.21059
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.16327
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.04365
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
3.02072
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.56686
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.50154
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.47078
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.38827
|
|
MMP1
|
matrix metallopeptidase 1
|
2.34665
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.21521
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.15733
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.15208
|
|
SNX7
|
sorting nexin 7
|
2.1451
|
|
SLC9A8
|
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
|
2.13785
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.07857
|
|
PMM2
|
phosphomannomutase 2
|
2.05221
|
|
TRAK2
|
trafficking protein, kinesin binding 2
|
2.03324
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DNM1L
|
dynamin 1-like
|
-6.43213
|
|
CCNB2
|
cyclin B2
|
-5.16585
|
|
TWF2
|
twinfilin actin binding protein 2
|
-4.18408
|
|
ZNF586
|
zinc finger protein 586
|
-3.58473
|
|
LDHD
|
lactate dehydrogenase D
|
-3.00153
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.97932
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.93657
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.86164
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.82831
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.60972
|
|
LGMN
|
legumain
|
-2.32293
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
-2.09052
|
|
PDE1B
|
phosphodiesterase 1B, calmodulin-dependent
|
-2.07942
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.0632
|
|
MTREX
|
Mtr4 exosome RNA helicase
|
-2.01844
|
