CRCGN012_HEPG2_24H:P19 Gene Set
Genes
56 genes differentially expressed following the CRCGN012_HEPG2_24H:P19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
7.06058
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
4.08099
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.88432
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.73581
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.70628
|
|
STK10
|
serine/threonine kinase 10
|
3.6808
|
|
E2F2
|
E2F transcription factor 2
|
3.48758
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
3.13739
|
|
CEP57
|
centrosomal protein 57kDa
|
2.98612
|
|
CRTAP
|
cartilage associated protein
|
2.96985
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.96056
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.91654
|
|
STIMATE
|
STIM activating enhancer
|
2.89809
|
|
MYLK
|
myosin light chain kinase
|
2.89087
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.81134
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.75202
|
|
CBR3
|
carbonyl reductase 3
|
2.74499
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.72737
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.7195
|
|
HEBP1
|
heme binding protein 1
|
2.48458
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.47002
|
|
CHN1
|
chimerin 1
|
2.4109
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.3161
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.224
|
|
SFTPB
|
surfactant protein B
|
2.22012
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.13984
|
|
RANBP6
|
RAN binding protein 6
|
2.07398
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ADI1
|
acireductone dioxygenase 1
|
-9.844
|
|
TRIB3
|
tribbles pseudokinase 3
|
-7.14908
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-6.32106
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.18044
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-3.99103
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.5166
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.43327
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-3.42181
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-3.39376
|
|
VAT1
|
vesicle amine transport 1
|
-3.17751
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-3.15407
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.14781
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-2.93413
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.91353
|
|
CCNB1
|
cyclin B1
|
-2.8166
|
|
TSPAN4
|
tetraspanin 4
|
-2.79335
|
|
GDF15
|
growth differentiation factor 15
|
-2.69091
|
|
RPS5
|
ribosomal protein S5
|
-2.68575
|
|
RAI14
|
retinoic acid induced 14
|
-2.66597
|
|
ENOPH1
|
enolase-phosphatase 1
|
-2.62598
|
|
LDHD
|
lactate dehydrogenase D
|
-2.53292
|
|
EGF
|
epidermal growth factor
|
-2.39605
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
-2.37726
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.31118
|
|
SIGIRR
|
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
|
-2.27022
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.2319
|
|
MRPS7
|
mitochondrial ribosomal protein S7
|
-2.1365
|
|
NUP85
|
nucleoporin 85kDa
|
-2.09926
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.08444
|
