| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | diallyl phthalate 19.7 um perturbation at 24 h in HEPG2 (Carcinogenome) |
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67 genes differentially expressed following the CRCGN012_HEPG2_24H:P20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 6.34849 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 6.05731 |
| CCNF | cyclin F | 4.6708 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.54976 |
| HEBP1 | heme binding protein 1 | 4.32877 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 4.06479 |
| E2F2 | E2F transcription factor 2 | 3.79076 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.56275 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.44057 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 3.30449 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.16873 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 3.10193 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 3.01587 |
| CSK | c-src tyrosine kinase | 2.99316 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.84169 |
| PPIE | peptidylprolyl isomerase E (cyclophilin E) | 2.78583 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.73598 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 2.54006 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 2.50183 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.48433 |
| GATA3 | GATA binding protein 3 | 2.41256 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 2.38559 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.38129 |
| FZD7 | frizzled class receptor 7 | 2.25805 |
| CERS4 | ceramide synthase 4 | 2.24122 |
| TWNK | twinkle mtDNA helicase | 2.2019 |
| MAP7 | microtubule-associated protein 7 | 2.18157 |
| ABHD6 | abhydrolase domain containing 6 | 2.12398 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 2.12385 |
| NOSIP | nitric oxide synthase interacting protein | 2.10694 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.10002 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -7.26162 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -5.94677 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | -4.85693 |
| NUP93 | nucleoporin 93kDa | -4.47955 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -4.03854 |
| DERA | deoxyribose-phosphate aldolase (putative) | -3.82597 |
| CCNB2 | cyclin B2 | -3.7688 |
| EGF | epidermal growth factor | -3.73997 |
| CDC20 | cell division cycle 20 | -3.66573 |
| TSPAN4 | tetraspanin 4 | -3.63364 |
| COG4 | component of oligomeric golgi complex 4 | -3.54863 |
| YME1L1 | YME1-like 1 ATPase | -3.48939 |
| TCERG1 | transcription elongation regulator 1 | -3.47057 |
| VAT1 | vesicle amine transport 1 | -3.29587 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.29028 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.28 |
| TRAP1 | TNF receptor-associated protein 1 | -3.2622 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.21071 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.19396 |
| BLCAP | bladder cancer associated protein | -2.95608 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.93399 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.92445 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -2.85372 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.65428 |
| TAF2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | -2.64151 |
| GDF15 | growth differentiation factor 15 | -2.61485 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -2.49573 |
| UBE3C | ubiquitin protein ligase E3C | -2.46266 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.31132 |
| APIP | APAF1 interacting protein | -2.27691 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.23194 |
| CCNB1 | cyclin B1 | -2.22868 |
| RPS5 | ribosomal protein S5 | -2.14654 |
| FAIM | Fas apoptotic inhibitory molecule | -2.13687 |
| TXNRD1 | thioredoxin reductase 1 | -2.13535 |
| PCNA | proliferating cell nuclear antigen | -2.12951 |