CRCGN012_HEPG2_24H:P22 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description diallyl phthalate 4.93 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

43 genes differentially expressed following the CRCGN012_HEPG2_24H:P22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RPP38 ribonuclease P/MRP 38kDa subunit 4.68844
ABHD6 abhydrolase domain containing 6 4.16754
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 3.62483
RPL39L ribosomal protein L39-like 3.23356
LPAR2 lysophosphatidic acid receptor 2 3.1624
HEBP1 heme binding protein 1 3.04484
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 3.00814
GSTZ1 glutathione S-transferase zeta 1 2.73009
NSDHL NAD(P) dependent steroid dehydrogenase-like 2.63966
TRAP1 TNF receptor-associated protein 1 2.59283
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.57662
CSK c-src tyrosine kinase 2.5623
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 2.24013
STXBP2 syntaxin binding protein 2 2.23618
HSPA1A heat shock 70kDa protein 1A 2.15977
SLC75A1 solute carrier family 75 member 1 2.11306
MPC2 mitochondrial pyruvate carrier 2 2.0911
UBQLN2 ubiquilin 2 2.05453
PPARG peroxisome proliferator-activated receptor gamma 2.04891
TBP TATA box binding protein 2.03328
HSPB1 heat shock 27kDa protein 1 2.00183

decreased expression

Symbol Name Standardized Value
TLCD3A TLC domain containing 3A -6.51013
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -4.85854
ISOC1 isochorismatase domain containing 1 -4.7248
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.40253
CDC20 cell division cycle 20 -4.30205
CDC25B cell division cycle 25B -4.24604
GOLT1B golgi transport 1B -4.13544
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -4.12287
ADI1 acireductone dioxygenase 1 -3.50451
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.69157
OXA1L oxidase (cytochrome c) assembly 1-like -2.68914
YME1L1 YME1-like 1 ATPase -2.67959
CASP7 caspase 7, apoptosis-related cysteine peptidase -2.6397
PEG10 paternally expressed 10 -2.60164
ERBB2 erb-b2 receptor tyrosine kinase 2 -2.57836
LDHD lactate dehydrogenase D -2.45255
ZMIZ1 zinc finger, MIZ-type containing 1 -2.24867
CCNB1 cyclin B1 -2.16838
SSBP2 single-stranded DNA binding protein 2 -2.13736
COG7 component of oligomeric golgi complex 7 -2.13021
ZNF586 zinc finger protein 586 -2.06917
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.05014