CRCGN012_HEPG2_24H:P23 Gene Set
Genes
38 genes differentially expressed following the CRCGN012_HEPG2_24H:P23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CSK
|
c-src tyrosine kinase
|
7.21889
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.34681
|
|
NMU
|
neuromedin U
|
4.23643
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
4.16991
|
|
EPHB2
|
EPH receptor B2
|
3.68628
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
3.38579
|
|
STIMATE
|
STIM activating enhancer
|
2.87181
|
|
RRAGA
|
Ras-related GTP binding A
|
2.75453
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.72523
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.595
|
|
CYCS
|
cytochrome c, somatic
|
2.59014
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
2.51421
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.44367
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
2.26334
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.19499
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.19112
|
|
LCN2
|
lipocalin 2
|
2.18413
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.07803
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
VAT1
|
vesicle amine transport 1
|
-4.10968
|
|
SMNDC1
|
survival motor neuron domain containing 1
|
-3.12461
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.87362
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.81026
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.81019
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.65191
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.61945
|
|
WASHC4
|
WASH complex subunit 4
|
-2.58166
|
|
DSG2
|
desmoglein 2
|
-2.53028
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.49703
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-2.4509
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.43542
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-2.43025
|
|
BDH1
|
3-hydroxybutyrate dehydrogenase, type 1
|
-2.41149
|
|
LDHD
|
lactate dehydrogenase D
|
-2.3973
|
|
MAP7
|
microtubule-associated protein 7
|
-2.35469
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.33355
|
|
TCTN1
|
tectonic family member 1
|
-2.21263
|
|
GNA11
|
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
|
-2.13611
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.12505
|
