CRCGN012_HEPG2_24H:P24 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description diallyl phthalate 1.23 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN012_HEPG2_24H:P24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RPP38 ribonuclease P/MRP 38kDa subunit 7.51507
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 7.25969
EVL Enah/Vasp-like 4.68527
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.2161
PRR15L proline rich 15-like 3.85105
CHN1 chimerin 1 3.79383
KCNK1 potassium channel, two pore domain subfamily K, member 1 3.60626
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.07817
E2F2 E2F transcription factor 2 2.69864
PTK2 protein tyrosine kinase 2 2.61263
C2CD5 C2 calcium-dependent domain containing 5 2.61004
CCNF cyclin F 2.5243
ATP11B ATPase, class VI, type 11B 2.52409
CIAO3 cytosolic iron-sulfur assembly component 3 2.50038
VAV3 vav 3 guanine nucleotide exchange factor 2.41764
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 2.35429
GLT8D1 glycosyltransferase 8 domain containing 1 2.11515
NSDHL NAD(P) dependent steroid dehydrogenase-like 2.03855
CDK6 cyclin-dependent kinase 6 2.02818
CCL2 chemokine (C-C motif) ligand 2 2.00281

decreased expression

Symbol Name Standardized Value
VAT1 vesicle amine transport 1 -4.64534
EGF epidermal growth factor -4.44305
ZNF586 zinc finger protein 586 -4.37687
CCNB2 cyclin B2 -4.02933
CASP7 caspase 7, apoptosis-related cysteine peptidase -3.01054
CDC20 cell division cycle 20 -2.94113
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.91597
ARID5B AT rich interactive domain 5B (MRF1-like) -2.85032
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -2.63119
CHMP4B charged multivesicular body protein 4B -2.60011
ITFG1 integrin alpha FG-GAP repeat containing 1 -2.52178
PDLIM1 PDZ and LIM domain 1 -2.37664
NGRN neugrin, neurite outgrowth associated -2.28818
MVP major vault protein -2.05107