CRCGN013_HEPG2_24H:A03 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description DMSO perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN013_HEPG2_24H:A03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
TREM1 triggering receptor expressed on myeloid cells 1 4.98848
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.46445
STIMATE STIM activating enhancer 3.20689
ADGRE5 adhesion G protein-coupled receptor E5 3.07769
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 3.06986
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 3.02374
CHN1 chimerin 1 3.01049
RAB11FIP1 RAB11 family interacting protein 1 (class I) 2.93406
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 2.76702
SFTPB surfactant protein B 2.70469
LYN LYN proto-oncogene, Src family tyrosine kinase 2.3391
SSBP2 single-stranded DNA binding protein 2 2.08799
CCNF cyclin F 2.0293
JADE2 jade family PHD finger 2 2.0228

decreased expression

Symbol Name Standardized Value
CCNB2 cyclin B2 -8.08113
CDC20 cell division cycle 20 -5.57176
TLCD3A TLC domain containing 3A -5.30678
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -4.42644
NRIP1 nuclear receptor interacting protein 1 -4.08896
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -3.73855
CD320 CD320 molecule -3.6171
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.50594
CRELD2 cysteine-rich with EGF-like domains 2 -3.49337
OXA1L oxidase (cytochrome c) assembly 1-like -3.22855
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.80617
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.65402
LDHD lactate dehydrogenase D -2.46413
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.32729
EGF epidermal growth factor -2.29025
TXNRD1 thioredoxin reductase 1 -2.12642
ZDHHC6 zinc finger, DHHC-type containing 6 -2.10698
ELOVL1 ELOVL fatty acid elongase 1 -2.05964
DHRS7 dehydrogenase/reductase (SDR family) member 7 -2.03054
IGFBP6 insulin-like growth factor binding protein 6 -2.02543