CRCGN013_HEPG2_24H:A04 Gene Set
Genes
44 genes differentially expressed following the CRCGN013_HEPG2_24H:A04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
7.247
|
|
INTS3
|
integrator complex subunit 3
|
3.80799
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.784
|
|
STIMATE
|
STIM activating enhancer
|
3.77398
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
3.75607
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.69549
|
|
KIT
|
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
|
3.65875
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.64108
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.61705
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.50007
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
3.18255
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.09161
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.03682
|
|
TGFB3
|
transforming growth factor, beta 3
|
2.83719
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.8046
|
|
PMM2
|
phosphomannomutase 2
|
2.79985
|
|
RRAGA
|
Ras-related GTP binding A
|
2.52732
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.29508
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.18231
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.06762
|
|
APOL3
|
apolipoprotein L, 3
|
2.06207
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-5.97447
|
|
GNAS
|
GNAS complex locus
|
-5.31424
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-3.78432
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.61369
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-3.52104
|
|
DSG2
|
desmoglein 2
|
-3.43958
|
|
TM9SF2
|
transmembrane 9 superfamily member 2
|
-3.42323
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.26338
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.93619
|
|
ALAS1
|
5'-aminolevulinate synthase 1
|
-2.80897
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-2.79913
|
|
CAB39
|
calcium binding protein 39
|
-2.59247
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.5135
|
|
TCTN1
|
tectonic family member 1
|
-2.37765
|
|
LAGE3
|
L antigen family, member 3
|
-2.3288
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.32129
|
|
IGF2BP2
|
insulin-like growth factor 2 mRNA binding protein 2
|
-2.2991
|
|
RNF167
|
ring finger protein 167
|
-2.28288
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.22716
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.20409
|
|
ZW10
|
zw10 kinetochore protein
|
-2.10227
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.06549
|
|
EBNA1BP2
|
EBNA1 binding protein 2
|
-2.03201
|
