| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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71 genes differentially expressed following the CRCGN013_HEPG2_24H:A05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PRR15L | proline rich 15-like | 4.31431 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.94346 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.78996 |
| EPHA3 | EPH receptor A3 | 3.60741 |
| ABHD4 | abhydrolase domain containing 4 | 3.44282 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 3.31296 |
| MAP7 | microtubule-associated protein 7 | 3.29325 |
| NOSIP | nitric oxide synthase interacting protein | 3.18512 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | 2.84865 |
| TBP | TATA box binding protein | 2.84229 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 2.81781 |
| MTERF3 | mitochondrial transcription termination factor 3 | 2.73804 |
| MELK | maternal embryonic leucine zipper kinase | 2.72969 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.72174 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.59112 |
| LCN2 | lipocalin 2 | 2.44783 |
| KIF20A | kinesin family member 20A | 2.41143 |
| CBR3 | carbonyl reductase 3 | 2.37982 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.35877 |
| CCDC86 | coiled-coil domain containing 86 | 2.35389 |
| CHN1 | chimerin 1 | 2.31137 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 2.28998 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 2.22115 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 2.17765 |
| ZNF692 | zinc finger protein 692 | 2.13309 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 2.09456 |
| MRPS2 | mitochondrial ribosomal protein S2 | 2.07772 |
| MMS19 | MMS19 nucleotide excision repair homolog (S. cerevisiae) | 2.03713 |
| EIF2B1 | eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa | 2.03687 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.02635 |
| LZTR1 | leucine-zipper-like transcription regulator 1 | 2.01451 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 2.00518 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 2.00266 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDC20 | cell division cycle 20 | -7.68857 |
| CCNB2 | cyclin B2 | -5.98517 |
| TLCD3A | TLC domain containing 3A | -5.98255 |
| ZNF586 | zinc finger protein 586 | -5.52473 |
| ZW10 | zw10 kinetochore protein | -5.1701 |
| LDHD | lactate dehydrogenase D | -5.08433 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.96555 |
| PCNA | proliferating cell nuclear antigen | -4.38837 |
| CCNB1 | cyclin B1 | -4.31681 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -4.01322 |
| PLK1 | polo-like kinase 1 | -3.83427 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -3.75805 |
| SLC35F2 | solute carrier family 35, member F2 | -3.31956 |
| ENOPH1 | enolase-phosphatase 1 | -3.27803 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -3.11661 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.03654 |
| MRPS16 | mitochondrial ribosomal protein S16 | -2.97037 |
| SNX11 | sorting nexin 11 | -2.96403 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | -2.76833 |
| USP22 | ubiquitin specific peptidase 22 | -2.74612 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.73548 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -2.41932 |
| IER3 | immediate early response 3 | -2.38549 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | -2.35816 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -2.35174 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.31816 |
| MTFR1 | mitochondrial fission regulator 1 | -2.30522 |
| CAB39 | calcium binding protein 39 | -2.25444 |
| FAIM | Fas apoptotic inhibitory molecule | -2.17862 |
| NGRN | neugrin, neurite outgrowth associated | -2.1634 |
| CDCA8 | cell division cycle associated 8 | -2.15813 |
| CRYZ | crystallin, zeta (quinone reductase) | -2.12527 |
| NUP93 | nucleoporin 93kDa | -2.1222 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -2.0759 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | -2.06224 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -2.05932 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -2.04405 |
| PRPF4 | pre-mRNA processing factor 4 | -2.04008 |
