CRCGN013_HEPG2_24H:A09 Gene Set
Genes
50 genes differentially expressed following the CRCGN013_HEPG2_24H:A09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.95162
|
|
E2F2
|
E2F transcription factor 2
|
4.08772
|
|
CTSL
|
cathepsin L
|
4.06219
|
|
MYLK
|
myosin light chain kinase
|
3.83186
|
|
SQOR
|
sulfide quinone oxidoreductase
|
3.64677
|
|
KLHL21
|
kelch-like family member 21
|
3.34038
|
|
INPP1
|
inositol polyphosphate-1-phosphatase
|
3.32721
|
|
LRP10
|
low density lipoprotein receptor-related protein 10
|
3.23438
|
|
ALAS1
|
5'-aminolevulinate synthase 1
|
3.17859
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
3.1308
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.80005
|
|
MVP
|
major vault protein
|
2.71686
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.52549
|
|
ICAM1
|
intercellular adhesion molecule 1
|
2.49342
|
|
PLS1
|
plastin 1
|
2.47873
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.45995
|
|
GATA3
|
GATA binding protein 3
|
2.4528
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.44261
|
|
IDE
|
insulin-degrading enzyme
|
2.4164
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.36884
|
|
CBR3
|
carbonyl reductase 3
|
2.34604
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
2.29997
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
2.2323
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.21023
|
|
PCBD1
|
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
|
2.21014
|
|
FHL2
|
four and a half LIM domains 2
|
2.18162
|
|
TXNRD1
|
thioredoxin reductase 1
|
2.14491
|
|
PRR15L
|
proline rich 15-like
|
2.12268
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.05778
|
|
RRAGA
|
Ras-related GTP binding A
|
2.0559
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-7.86669
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.22866
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.16083
|
|
GNAS
|
GNAS complex locus
|
-4.85843
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.04768
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.53646
|
|
LDHD
|
lactate dehydrogenase D
|
-3.47818
|
|
CDC20
|
cell division cycle 20
|
-3.18699
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.92567
|
|
UBE2C
|
ubiquitin-conjugating enzyme E2C
|
-2.76633
|
|
CHEK1
|
checkpoint kinase 1
|
-2.48507
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.31091
|
|
CDC25B
|
cell division cycle 25B
|
-2.2144
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.18106
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.1588
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.10472
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.08669
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.05396
|
|
DECR1
|
2,4-dienoyl CoA reductase 1, mitochondrial
|
-2.04179
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.012
|
