CRCGN013_HEPG2_24H:A10 Gene Set
Genes
47 genes differentially expressed following the CRCGN013_HEPG2_24H:A10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHN1
|
chimerin 1
|
5.10643
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.51371
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.36619
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
4.20663
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.12177
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.03552
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
3.93455
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
3.67023
|
|
MAN2B1
|
mannosidase, alpha, class 2B, member 1
|
2.74307
|
|
CTSL
|
cathepsin L
|
2.67284
|
|
SFTPB
|
surfactant protein B
|
2.58665
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.48175
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.37888
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.34233
|
|
MVP
|
major vault protein
|
2.3423
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.24287
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.12773
|
|
NFKB1
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
|
2.09961
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.04188
|
|
PRR15L
|
proline rich 15-like
|
2.02445
|
|
FHL2
|
four and a half LIM domains 2
|
2.01524
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-6.71023
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.63759
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-3.93829
|
|
RUVBL1
|
RuvB-like AAA ATPase 1
|
-3.76385
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.58656
|
|
GDF15
|
growth differentiation factor 15
|
-3.58314
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-3.14836
|
|
CCNB2
|
cyclin B2
|
-3.11963
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.10766
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-3.02838
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.99738
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-2.72382
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.65248
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-2.58351
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.55136
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.54654
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.51507
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.48262
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.42981
|
|
FDFT1
|
farnesyl-diphosphate farnesyltransferase 1
|
-2.38117
|
|
EDN1
|
endothelin 1
|
-2.37518
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.27421
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
-2.22669
|
|
CLXN
|
calaxin
|
-2.15154
|
|
LDHD
|
lactate dehydrogenase D
|
-2.02349
|
|
APOE
|
apolipoprotein E
|
-2.00591
|
