CRCGN013_HEPG2_24H:A11 Gene Set
Genes
37 genes differentially expressed following the CRCGN013_HEPG2_24H:A11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.44843
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
4.82371
|
|
MAP7
|
microtubule-associated protein 7
|
3.72867
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.49176
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.37898
|
|
STK10
|
serine/threonine kinase 10
|
3.19295
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.14134
|
|
MYLK
|
myosin light chain kinase
|
3.06893
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.94393
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.7482
|
|
MICALL1
|
MICAL-like 1
|
2.71134
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.65308
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.56768
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.50358
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.30851
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.00449
|
|
PMM2
|
phosphomannomutase 2
|
2.00002
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NGRN
|
neugrin, neurite outgrowth associated
|
-4.46462
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-3.91938
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.67397
|
|
SCAND1
|
SCAN domain containing 1
|
-3.64326
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.6419
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.63014
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-3.56798
|
|
GDF15
|
growth differentiation factor 15
|
-3.55786
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.12752
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.99782
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.99692
|
|
CDC20
|
cell division cycle 20
|
-2.98825
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.97746
|
|
VAT1
|
vesicle amine transport 1
|
-2.96574
|
|
CCNB2
|
cyclin B2
|
-2.38448
|
|
BCL10
|
B-cell CLL/lymphoma 10
|
-2.27618
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.15661
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.14989
|
|
TBCB
|
tubulin folding cofactor B
|
-2.14229
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.11738
|
