CRCGN013_HEPG2_24H:A12 Gene Set
Genes
45 genes differentially expressed following the CRCGN013_HEPG2_24H:A12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.58254
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
3.91858
|
|
STIMATE
|
STIM activating enhancer
|
3.80693
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.70491
|
|
JADE2
|
jade family PHD finger 2
|
3.64826
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
3.61361
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
3.58
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.54567
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.54357
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.47886
|
|
UBQLN2
|
ubiquilin 2
|
3.37686
|
|
CHN1
|
chimerin 1
|
3.36019
|
|
UBR7
|
ubiquitin protein ligase E3 component n-recognin 7 (putative)
|
3.29007
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
3.04462
|
|
CYCS
|
cytochrome c, somatic
|
2.96979
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.78497
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.72371
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.62935
|
|
ZNF589
|
zinc finger protein 589
|
2.43341
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.39107
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.36257
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.35972
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.24963
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
2.19869
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.14491
|
|
LDHD
|
lactate dehydrogenase D
|
-3.69686
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.5734
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.4992
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-3.37665
|
|
CAB39
|
calcium binding protein 39
|
-3.06974
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.02433
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-2.96473
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.86248
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.84936
|
|
EGF
|
epidermal growth factor
|
-2.78162
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.72509
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.68549
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.59435
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-2.51239
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.50026
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.45946
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.4355
|
|
RAI14
|
retinoic acid induced 14
|
-2.38573
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.24343
|
|
RNF167
|
ring finger protein 167
|
-2.17217
|
