CRCGN013_HEPG2_24H:A13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methyleugenol 40.4 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

25 genes differentially expressed following the CRCGN013_HEPG2_24H:A13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 7.01511
TREM1 triggering receptor expressed on myeloid cells 1 4.56146
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 4.41461
SSBP2 single-stranded DNA binding protein 2 3.68701
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.7731
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.75511
MAP7 microtubule-associated protein 7 2.52706
RRAGA Ras-related GTP binding A 2.37476
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.20088
CTSL cathepsin L 2.17691
LPAR2 lysophosphatidic acid receptor 2 2.14126
RAB4A RAB4A, member RAS oncogene family 2.04339

decreased expression

Symbol Name Standardized Value
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.82387
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.47802
LDHD lactate dehydrogenase D -4.46395
EGF epidermal growth factor -3.88569
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.72431
TWF2 twinfilin actin binding protein 2 -3.60319
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -3.50409
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -2.90518
VAT1 vesicle amine transport 1 -2.88244
UGDH UDP-glucose 6-dehydrogenase -2.48679
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.47838
TEX10 testis expressed 10 -2.21167
CRELD2 cysteine-rich with EGF-like domains 2 -2.0943