CRCGN013_HEPG2_24H:A14 Gene Set
Genes
42 genes differentially expressed following the CRCGN013_HEPG2_24H:A14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
8.83233
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.74447
|
|
PLS1
|
plastin 1
|
4.45486
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
4.25361
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.97387
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.68864
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.39011
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
3.10388
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
3.07972
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.79252
|
|
LCN2
|
lipocalin 2
|
2.74084
|
|
GPATCH8
|
G patch domain containing 8
|
2.38637
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.3439
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.25783
|
|
UQCR11
|
ubiquinol-cytochrome c reductase, complex III subunit XI
|
2.24444
|
|
EVL
|
Enah/Vasp-like
|
2.2257
|
|
SHB
|
Src homology 2 domain containing adaptor protein B
|
2.1958
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.18069
|
|
SFTPB
|
surfactant protein B
|
2.16923
|
|
RETREG3
|
reticulophagy regulator family member 3
|
2.13885
|
|
PIEZO2
|
piezo-type mechanosensitive ion channel component 2
|
2.13687
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.12293
|
|
RBMS3
|
RNA binding motif, single stranded interacting protein 3
|
2.11332
|
|
GREB1L
|
growth regulation by estrogen in breast cancer-like
|
2.01343
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.45401
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-4.86365
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.27778
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.88446
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.87704
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.34282
|
|
GDF15
|
growth differentiation factor 15
|
-3.2425
|
|
ERC2
|
ELKS/RAB6-interacting/CAST family member 2
|
-3.16451
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.03175
|
|
EGF
|
epidermal growth factor
|
-2.7991
|
|
EDN1
|
endothelin 1
|
-2.68947
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.57977
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.52113
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.42052
|
|
ETV6
|
ets variant 6
|
-2.22764
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
-2.1427
|
|
SNCB
|
synuclein, beta
|
-2.14198
|
|
TBC1D15
|
TBC1 domain family, member 15
|
-2.0042
|
