CRCGN013_HEPG2_24H:A16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methyleugenol 5.05 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

53 genes differentially expressed following the CRCGN013_HEPG2_24H:A16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 5.7735
PRKCH protein kinase C, eta 4.77086
CYCS cytochrome c, somatic 4.52551
RPL39L ribosomal protein L39-like 4.31837
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 4.16999
C2CD2 C2 calcium-dependent domain containing 2 3.88367
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.7902
CHMP6 charged multivesicular body protein 6 3.75515
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.75299
E2F2 E2F transcription factor 2 3.65193
CCL2 chemokine (C-C motif) ligand 2 3.63311
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 3.60868
COL4A1 collagen, type IV, alpha 1 3.52464
ADRB2 adrenoceptor beta 2, surface 3.38834
CHN1 chimerin 1 2.89267
GSTZ1 glutathione S-transferase zeta 1 2.87196
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 2.72768
NNT nicotinamide nucleotide transhydrogenase 2.70047
TIAM1 T-cell lymphoma invasion and metastasis 1 2.5847
TBP TATA box binding protein 2.5794
PEX11A peroxisomal biogenesis factor 11 alpha 2.46709
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.34062
PARP1 poly (ADP-ribose) polymerase 1 2.33509
LOXL1 lysyl oxidase-like 1 2.30733
PKN1 protein kinase N1 2.2424
HSPA1A heat shock 70kDa protein 1A 2.23287
OLFML2B olfactomedin-like 2B 2.12697
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.10722
EGF epidermal growth factor 2.09423
OXCT1 3-oxoacid CoA transferase 1 2.07376
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.02475
INSIG1 insulin induced gene 1 2.01675
CCNF cyclin F 2.00466

decreased expression

Symbol Name Standardized Value
DUSP6 dual specificity phosphatase 6 -4.22414
CCNB1 cyclin B1 -3.84259
DHRS7 dehydrogenase/reductase (SDR family) member 7 -3.71146
OXA1L oxidase (cytochrome c) assembly 1-like -3.52218
CDC20 cell division cycle 20 -3.28252
TCTN1 tectonic family member 1 -3.12794
CASP7 caspase 7, apoptosis-related cysteine peptidase -3.0654
FGFR4 fibroblast growth factor receptor 4 -2.84228
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.62663
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.62483
FABP5 fatty acid binding protein 5 (psoriasis-associated) -2.32237
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.30757
NRIP1 nuclear receptor interacting protein 1 -2.23748
SPAG4 sperm associated antigen 4 -2.23639
LAGE3 L antigen family, member 3 -2.22015
CAB39 calcium binding protein 39 -2.19803
NVL nuclear VCP-like -2.08067
COL9A2 collagen, type IX, alpha 2 -2.06628
RPS5 ribosomal protein S5 -2.02991
KXD1 KxDL motif containing 1 -2.0042