CRCGN013_HEPG2_24H:A18 Gene Set
Genes
49 genes differentially expressed following the CRCGN013_HEPG2_24H:A18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.83881
|
|
CHN1
|
chimerin 1
|
6.01727
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
5.45784
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.84748
|
|
STIMATE
|
STIM activating enhancer
|
3.57467
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.27296
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
3.24567
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
3.04565
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.96043
|
|
UBQLN2
|
ubiquilin 2
|
2.84146
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.75536
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.75333
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.63248
|
|
MAP7
|
microtubule-associated protein 7
|
2.63083
|
|
LCN2
|
lipocalin 2
|
2.54242
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.43871
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.40127
|
|
ACVR2B
|
activin A receptor, type IIB
|
2.37634
|
|
CEP57
|
centrosomal protein 57kDa
|
2.33137
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.31412
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.23106
|
|
SFTPB
|
surfactant protein B
|
2.22972
|
|
PRDM1
|
PR domain containing 1, with ZNF domain
|
2.19301
|
|
AIM2
|
absent in melanoma 2
|
2.18048
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
2.10354
|
|
CXCR1
|
chemokine (C-X-C motif) receptor 1
|
2.0877
|
|
MCTP1
|
multiple C2 domains, transmembrane 1
|
2.00285
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
GNAS
|
GNAS complex locus
|
-5.32245
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.63494
|
|
CCNB1
|
cyclin B1
|
-4.22781
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.14421
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.88074
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.77598
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.34299
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.26137
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.19941
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.06049
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.84737
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.42905
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.41083
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.35164
|
|
GDF15
|
growth differentiation factor 15
|
-2.3413
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.33154
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.31051
|
|
FXYD7
|
FXYD domain containing ion transport regulator 7
|
-2.02447
|
|
PRAME
|
preferentially expressed antigen in melanoma
|
-2.02383
|
|
APH1A
|
APH1A gamma secretase subunit
|
-2.01792
|
|
RNF167
|
ring finger protein 167
|
-2.00764
|
