CRCGN013_HEPG2_24H:A21 Gene Set
Genes
43 genes differentially expressed following the CRCGN013_HEPG2_24H:A21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
7.41162
|
|
CHMP6
|
charged multivesicular body protein 6
|
7.21457
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
5.66256
|
|
CHN1
|
chimerin 1
|
5.3192
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
5.11767
|
|
LCN2
|
lipocalin 2
|
4.46231
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
3.7385
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.65072
|
|
CDC45
|
cell division cycle 45
|
3.17987
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.02077
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
2.96412
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.89749
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.8744
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.79033
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.74043
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.56488
|
|
ZNF589
|
zinc finger protein 589
|
2.51017
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.46577
|
|
NOTCH1
|
notch 1
|
2.35861
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.23406
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC20
|
cell division cycle 20
|
-4.80013
|
|
NUP85
|
nucleoporin 85kDa
|
-4.35391
|
|
RAI14
|
retinoic acid induced 14
|
-3.76025
|
|
GNAS
|
GNAS complex locus
|
-3.51042
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.32898
|
|
STUB1
|
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
|
-2.68594
|
|
LDHD
|
lactate dehydrogenase D
|
-2.67426
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.48702
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.451
|
|
SNX11
|
sorting nexin 11
|
-2.41658
|
|
EGF
|
epidermal growth factor
|
-2.41293
|
|
TRAPPC6A
|
trafficking protein particle complex 6A
|
-2.39427
|
|
GDF15
|
growth differentiation factor 15
|
-2.33475
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.32798
|
|
CCNB2
|
cyclin B2
|
-2.29038
|
|
CDR2L
|
cerebellar degeneration-related protein 2-like
|
-2.28923
|
|
MRPS7
|
mitochondrial ribosomal protein S7
|
-2.2338
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.22527
|
|
COG2
|
component of oligomeric golgi complex 2
|
-2.21243
|
|
NAT9
|
N-acetyltransferase 9 (GCN5-related, putative)
|
-2.21207
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.04929
|
|
WASHC4
|
WASH complex subunit 4
|
-2.04858
|
|
ELOVL1
|
ELOVL fatty acid elongase 1
|
-2.03081
|