| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | phenformin 4.97 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
73 genes differentially expressed following the CRCGN013_HEPG2_24H:A22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 5.88348 |
| FCHO1 | FCH domain only 1 | 4.97625 |
| TBP | TATA box binding protein | 4.6932 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 3.7512 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 3.2733 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.2608 |
| FZD7 | frizzled class receptor 7 | 3.2165 |
| PLSCR1 | phospholipid scramblase 1 | 3.21572 |
| CHEK2 | checkpoint kinase 2 | 3.17378 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.9189 |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) | 2.64225 |
| FPGS | folylpolyglutamate synthase | 2.4945 |
| ZKSCAN7 | zinc finger with KRAB and SCAN domains 7 | 2.45955 |
| CERK | ceramide kinase | 2.4574 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.41542 |
| ENY2 | enhancer of yellow 2 homolog (Drosophila) | 2.4039 |
| CNPY3 | canopy FGF signaling regulator 3 | 2.38695 |
| SULF1 | sulfatase 1 | 2.36993 |
| HOXA5 | homeobox A5 | 2.3627 |
| RBKS | ribokinase | 2.35695 |
| NUP85 | nucleoporin 85kDa | 2.34215 |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 | 2.30675 |
| PTK2 | protein tyrosine kinase 2 | 2.2112 |
| OTUD3 | OTU deubiquitinase 3 | 2.1756 |
| SNX7 | sorting nexin 7 | 2.1695 |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 | 2.15385 |
| GRAMD2B | GRAM domain containing 2B | 2.1453 |
| MMP2 | matrix metallopeptidase 2 | 2.1416 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 2.12105 |
| FZD4 | frizzled class receptor 4 | 2.1127 |
| COA4 | cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae) | 2.09205 |
| EED | embryonic ectoderm development | 2.08633 |
| PXDC1 | PX domain containing 1 | 2.06 |
| PIGB | phosphatidylinositol glycan anchor biosynthesis, class B | 2.0512 |
| POLR2K | polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa | 2.00627 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NVL | nuclear VCP-like | -5.47275 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -5.28605 |
| LDHD | lactate dehydrogenase D | -4.83035 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -4.7259 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.6316 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -4.6166 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.46955 |
| NCK1 | NCK adaptor protein 1 | -4.26178 |
| RPS5 | ribosomal protein S5 | -4.09745 |
| CCNB1 | cyclin B1 | -3.8875 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | -3.82055 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.7973 |
| NGRN | neugrin, neurite outgrowth associated | -3.6919 |
| MTFR1 | mitochondrial fission regulator 1 | -3.62162 |
| ZNF586 | zinc finger protein 586 | -3.3618 |
| CCNB2 | cyclin B2 | -3.2298 |
| ZNF274 | zinc finger protein 274 | -3.1649 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -2.9003 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.77665 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -2.7264 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | -2.71165 |
| FBXO28 | F-box protein 28 | -2.6041 |
| MICU1 | mitochondrial calcium uptake 1 | -2.5615 |
| TEX10 | testis expressed 10 | -2.36835 |
| LSR | lipolysis stimulated lipoprotein receptor | -2.28955 |
| MRPS16 | mitochondrial ribosomal protein S16 | -2.26815 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.23485 |
| ATG4A | autophagy related 4A, cysteine peptidase | -2.17575 |
| TRPV2 | transient receptor potential cation channel, subfamily V, member 2 | -2.16965 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.15465 |
| PTCD2 | pentatricopeptide repeat domain 2 | -2.10895 |
| COL7A1 | collagen, type VII, alpha 1 | -2.08655 |
| COMMD3-BMI1 | COMMD3-BMI1 readthrough | -2.08365 |
| FOSL1 | FOS-like antigen 1 | -2.06505 |
| ABCB7 | ATP-binding cassette, sub-family B (MDR/TAP), member 7 | -2.0298 |
| RNF11 | ring finger protein 11 | -2.0238 |
| TRAP1 | TNF receptor-associated protein 1 | -2.01895 |
| XPO4 | exportin 4 | -2.0062 |
