CRCGN013_HEPG2_24H:A23 Gene Set
Genes
31 genes differentially expressed following the CRCGN013_HEPG2_24H:A23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.67315
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.31557
|
|
PROS1
|
protein S (alpha)
|
4.02048
|
|
UBR7
|
ubiquitin protein ligase E3 component n-recognin 7 (putative)
|
3.59545
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.38642
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.99572
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.99006
|
|
CBR3
|
carbonyl reductase 3
|
2.91778
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.91276
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
2.90935
|
|
UBQLN2
|
ubiquilin 2
|
2.83132
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.34829
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.34613
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.28572
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.2205
|
|
CYCS
|
cytochrome c, somatic
|
2.06335
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-6.23607
|
|
LDHD
|
lactate dehydrogenase D
|
-4.90718
|
|
CCNB2
|
cyclin B2
|
-4.86894
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-4.8504
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.16355
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.51986
|
|
PYGL
|
phosphorylase, glycogen, liver
|
-2.58833
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.46955
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.37781
|
|
GRN
|
granulin
|
-2.34241
|
|
RNF167
|
ring finger protein 167
|
-2.29687
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.22702
|
|
TLR4
|
toll-like receptor 4
|
-2.11839
|
|
GNAS
|
GNAS complex locus
|
-2.03548
|
|
ARHGAP10
|
Rho GTPase activating protein 10
|
-2.0243
|