CRCGN013_HEPG2_24H:B03 Gene Set
Genes
26 genes differentially expressed following the CRCGN013_HEPG2_24H:B03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
5.31672
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
4.87571
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
4.6721
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.49163
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
3.2008
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
3.0966
|
|
ICAM1
|
intercellular adhesion molecule 1
|
2.97236
|
|
JADE2
|
jade family PHD finger 2
|
2.93113
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
2.78154
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.32307
|
|
CCNF
|
cyclin F
|
2.11649
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.06406
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-6.42839
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.82808
|
|
CCNB2
|
cyclin B2
|
-3.66218
|
|
HMG20B
|
high mobility group 20B
|
-3.6402
|
|
EGF
|
epidermal growth factor
|
-3.60987
|
|
CDC25B
|
cell division cycle 25B
|
-3.52786
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
-3.15394
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.54965
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.45402
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.38305
|
|
ZNF134
|
zinc finger protein 134
|
-2.36612
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.29704
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.21263
|
|
FAM13A
|
family with sequence similarity 13, member A
|
-2.093
|