CRCGN013_HEPG2_24H:B05 Gene Set
Genes
44 genes differentially expressed following the CRCGN013_HEPG2_24H:B05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
6.8333
|
|
UBQLN2
|
ubiquilin 2
|
5.10401
|
|
E2F2
|
E2F transcription factor 2
|
4.9559
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.95248
|
|
RPL39L
|
ribosomal protein L39-like
|
4.93315
|
|
MYLK
|
myosin light chain kinase
|
4.91185
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
4.91098
|
|
KLHL21
|
kelch-like family member 21
|
4.68012
|
|
ATP11B
|
ATPase, class VI, type 11B
|
4.59896
|
|
LCN2
|
lipocalin 2
|
4.56665
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.57201
|
|
CYCS
|
cytochrome c, somatic
|
3.57164
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.82579
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.56971
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.40427
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.37197
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.3688
|
|
JADE2
|
jade family PHD finger 2
|
2.32428
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.24399
|
|
UGT8
|
UDP glycosyltransferase 8
|
2.24086
|
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
2.12727
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.09766
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-7.93846
|
|
TRIB3
|
tribbles pseudokinase 3
|
-7.89413
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-5.32413
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-5.15809
|
|
TUBB6
|
tubulin, beta 6 class V
|
-5.11332
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.78385
|
|
CCNB2
|
cyclin B2
|
-3.44471
|
|
GNAS
|
GNAS complex locus
|
-3.41787
|
|
SNX11
|
sorting nexin 11
|
-2.89854
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.66824
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.43731
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.37682
|
|
SCAND1
|
SCAN domain containing 1
|
-2.34583
|
|
STK16
|
serine/threonine kinase 16
|
-2.29209
|
|
GDF15
|
growth differentiation factor 15
|
-2.28093
|
|
TLR4
|
toll-like receptor 4
|
-2.28002
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
-2.22166
|
|
AHR
|
aryl hydrocarbon receptor
|
-2.17907
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.15781
|
|
TFPI2
|
tissue factor pathway inhibitor 2
|
-2.06107
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.04465
|
|
GOLGA8F
|
golgin A8 family, member F
|
-2.03339
|
