| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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64 genes differentially expressed following the CRCGN013_HEPG2_24H:B06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYLK | myosin light chain kinase | 10.0 |
| PPARG | peroxisome proliferator-activated receptor gamma | 7.29327 |
| UBQLN2 | ubiquilin 2 | 5.6255 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 5.49533 |
| MAP7 | microtubule-associated protein 7 | 5.37301 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.9279 |
| RRAGA | Ras-related GTP binding A | 4.18856 |
| LCN2 | lipocalin 2 | 3.51263 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 3.37585 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.2367 |
| CBR3 | carbonyl reductase 3 | 3.21593 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.13488 |
| MMP1 | matrix metallopeptidase 1 | 3.08734 |
| MSRA | methionine sulfoxide reductase A | 2.81602 |
| NOTCH1 | notch 1 | 2.78176 |
| SH3D19 | SH3 domain containing 19 | 2.6511 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.63592 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.50799 |
| RPL39L | ribosomal protein L39-like | 2.45117 |
| GATA2 | GATA binding protein 2 | 2.37376 |
| STIMATE | STIM activating enhancer | 2.34166 |
| VAV3 | vav 3 guanine nucleotide exchange factor | 2.33858 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 2.30337 |
| PXMP2 | peroxisomal membrane protein 2, 22kDa | 2.28413 |
| VCPKMT | valosin containing protein lysine (K) methyltransferase | 2.27646 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.23471 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.20887 |
| NOSIP | nitric oxide synthase interacting protein | 2.13604 |
| ACO1 | aconitase 1, soluble | 2.09085 |
| ABCA6 | ATP-binding cassette, sub-family A (ABC1), member 6 | 2.07592 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric | 2.06124 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide | 2.01231 |
| MORC3 | MORC family CW-type zinc finger 3 | 2.00023 |
| Symbol | Name | Standardized Value |
|---|---|---|
| THAP11 | THAP domain containing 11 | -5.74083 |
| PCNA | proliferating cell nuclear antigen | -5.29978 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -5.23756 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.11317 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -5.08122 |
| CCNB2 | cyclin B2 | -4.90762 |
| CD320 | CD320 molecule | -4.62972 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.29677 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.8217 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -3.6419 |
| ADI1 | acireductone dioxygenase 1 | -3.6371 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.61171 |
| GNAS | GNAS complex locus | -3.45422 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.38388 |
| VDAC1 | voltage-dependent anion channel 1 | -3.157 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -2.98132 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.9527 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.75202 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.65409 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -2.5536 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.4462 |
| NGRN | neugrin, neurite outgrowth associated | -2.42881 |
| HMG20B | high mobility group 20B | -2.38445 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.33672 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -2.27548 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.1876 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -2.13293 |
| ABHD11 | abhydrolase domain containing 11 | -2.0739 |
| ZMAT3 | zinc finger, matrin-type 3 | -2.05438 |
| PGC | progastricsin (pepsinogen C) | -2.03806 |
| TEX10 | testis expressed 10 | -2.00486 |
