CRCGN013_HEPG2_24H:B11 Gene Set
Genes
36 genes differentially expressed following the CRCGN013_HEPG2_24H:B11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
3.49903
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
3.48337
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.42283
|
|
HDGFL3
|
HDGF like 3
|
2.98882
|
|
EVL
|
Enah/Vasp-like
|
2.90653
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.8206
|
|
NFKBIE
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
|
2.79497
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.7346
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
2.72447
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.44147
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.35838
|
|
ZNF589
|
zinc finger protein 589
|
2.28523
|
|
PRR15L
|
proline rich 15-like
|
2.26127
|
|
GATA2
|
GATA binding protein 2
|
2.16645
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.15638
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.65423
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-5.0853
|
|
GNAS
|
GNAS complex locus
|
-4.76985
|
|
CCNB2
|
cyclin B2
|
-4.31933
|
|
THAP11
|
THAP domain containing 11
|
-3.9785
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.32083
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.3185
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.206
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-3.15657
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-3.14813
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.9976
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-2.86987
|
|
GDF15
|
growth differentiation factor 15
|
-2.7283
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.62467
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.57723
|
|
HMG20B
|
high mobility group 20B
|
-2.28627
|
|
DCK
|
deoxycytidine kinase
|
-2.1277
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.04714
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.01087
|
|
CD96
|
CD96 molecule
|
-2.0084
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.00037
|
