CRCGN013_HEPG2_24H:B12 Gene Set
Genes
50 genes differentially expressed following the CRCGN013_HEPG2_24H:B12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PROS1
|
protein S (alpha)
|
4.25518
|
|
RRAGA
|
Ras-related GTP binding A
|
4.25378
|
|
CRTAP
|
cartilage associated protein
|
4.07578
|
|
STIMATE
|
STIM activating enhancer
|
4.0445
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.99974
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.91693
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.77935
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.72174
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.69547
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
3.66122
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.41143
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.17441
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.91618
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.89885
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.76225
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.72025
|
|
MAP7
|
microtubule-associated protein 7
|
2.47034
|
|
FRAT1
|
frequently rearranged in advanced T-cell lymphomas 1
|
2.42411
|
|
NUP133
|
nucleoporin 133kDa
|
2.40956
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.35416
|
|
PRKCQ
|
protein kinase C, theta
|
2.22118
|
|
TCTA
|
T-cell leukemia translocation altered
|
2.20783
|
|
CXCL9
|
chemokine (C-X-C motif) ligand 9
|
2.18183
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.15208
|
|
AGBL5
|
ATP/GTP binding protein-like 5
|
2.06336
|
|
JADE2
|
jade family PHD finger 2
|
2.05633
|
|
TLR4
|
toll-like receptor 4
|
2.0068
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-6.26421
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.27312
|
|
TRIB3
|
tribbles pseudokinase 3
|
-5.1739
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.58258
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
-4.10785
|
|
ZNF586
|
zinc finger protein 586
|
-4.09396
|
|
TRAP1
|
TNF receptor-associated protein 1
|
-3.84044
|
|
LDHD
|
lactate dehydrogenase D
|
-3.78016
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.53069
|
|
GNAS
|
GNAS complex locus
|
-3.41137
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.39307
|
|
GDF15
|
growth differentiation factor 15
|
-3.19371
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.15184
|
|
NUP85
|
nucleoporin 85kDa
|
-3.00347
|
|
DCK
|
deoxycytidine kinase
|
-2.8765
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.80825
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.74551
|
|
AKAP8
|
A kinase (PRKA) anchor protein 8
|
-2.47525
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-2.28433
|
|
CERS6
|
ceramide synthase 6
|
-2.22611
|
|
RBM15
|
RNA binding motif protein 15
|
-2.20499
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.13945
|
|
USP21
|
ubiquitin specific peptidase 21
|
-2.0517
|
