CRCGN013_HEPG2_24H:B13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description p-nitrosodiphenylamine 40.2 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

619 genes differentially expressed following the CRCGN013_HEPG2_24H:B13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
CNPY3 canopy FGF signaling regulator 3 9.56552
HSPA1A heat shock 70kDa protein 1A 9.32443
LRP10 low density lipoprotein receptor-related protein 10 7.03657
LCN2 lipocalin 2 6.61921
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 6.59567
EGR1 early growth response 1 6.59003
FOSL1 FOS-like antigen 1 5.85229
KIFBP kinesin family binding protein 5.72038
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha 5.69548
BAG3 BCL2-associated athanogene 3 5.60921
ATP11B ATPase, class VI, type 11B 5.56131
INPP1 inositol polyphosphate-1-phosphatase 5.49386
TENT4A terminal nucleotidyltransferase 4A 5.4503
FOS FBJ murine osteosarcoma viral oncogene homolog 5.43972
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 5.40033
GADD45B growth arrest and DNA-damage-inducible, beta 5.29398
H2BC12 H2B clustered histone 12 5.10776
TUBB6 tubulin, beta 6 class V 4.92669
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 4.86847
TIMP2 TIMP metallopeptidase inhibitor 2 4.83181
TXNRD1 thioredoxin reductase 1 4.82849
ADGRE5 adhesion G protein-coupled receptor E5 4.60166
HSPA1B heat shock 70kDa protein 1B 4.57866
TESK1 testis-specific kinase 1 4.5464
HMOX1 heme oxygenase 1 4.52723
SQOR sulfide quinone oxidoreductase 4.41126
FOXO3 forkhead box O3 4.36741
ABHD4 abhydrolase domain containing 4 4.31646
CHN1 chimerin 1 4.30555
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 4.2645
GADD45A growth arrest and DNA-damage-inducible, alpha 4.23218
ALAS1 5'-aminolevulinate synthase 1 4.22415
IER3 immediate early response 3 4.18565
UBQLN2 ubiquilin 2 4.16694
HSPA6 heat shock 70kDa protein 6 (HSP70B') 4.10382
CTSL cathepsin L 3.94847
BAD BCL2-associated agonist of cell death 3.87715
NR1H2 nuclear receptor subfamily 1, group H, member 2 3.69881
H2BC21 H2B clustered histone 21 3.64774
ATF3 activating transcription factor 3 3.64032
RNMT RNA (guanine-7-) methyltransferase 3.63291
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 3.59792
CDK7 cyclin-dependent kinase 7 3.59545
SMIM40 small integral membrane protein 40 3.54584
ARID4B AT rich interactive domain 4B (RBP1-like) 3.51535
SHB Src homology 2 domain containing adaptor protein B 3.48423
IER2 immediate early response 2 3.46042
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 3.44588
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 3.43551
PPP1R13B protein phosphatase 1, regulatory subunit 13B 3.41186
FOXD1 forkhead box D1 3.3768
TBPL1 TBP-like 1 3.37254
SNX13 sorting nexin 13 3.32891
IFNAR1 interferon (alpha, beta and omega) receptor 1 3.29034
PRKCQ protein kinase C, theta 3.28337
PRR15L proline rich 15-like 3.27101
MAP3K14 mitogen-activated protein kinase kinase kinase 14 3.26827
KIF5C kinesin family member 5C 3.26098
RAB21 RAB21, member RAS oncogene family 3.25074
NIT1 nitrilase 1 3.24997
ZFP36 ZFP36 ring finger protein 3.20036
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 3.18804
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 3.18546
ARL14 ADP-ribosylation factor-like 14 3.17573
SFTPB surfactant protein B 3.16837
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 3.16336
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 3.15447
KLF11 Kruppel-like factor 11 3.11824
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 3.10746
MCOLN1 mucolipin 1 3.10553
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 3.09788
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 3.06285
NOTCH1 notch 1 3.05218
TRIB1 tribbles pseudokinase 1 3.0513
UBE2A ubiquitin-conjugating enzyme E2A 3.04536
YIPF3 Yip1 domain family, member 3 3.03903
TERF2IP telomeric repeat binding factor 2, interacting protein 3.03542
ZNF440 zinc finger protein 440 3.03537
PRRX1 paired related homeobox 1 2.96847
JUN jun proto-oncogene 2.9596
CCNA1 cyclin A1 2.95761
PLP2 proteolipid protein 2 (colonic epithelium-enriched) 2.95497
HSPB1 heat shock 27kDa protein 1 2.93283
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide 2.9312
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.92271
FCHO1 FCH domain only 1 2.90962
SSBP2 single-stranded DNA binding protein 2 2.90931
CEP57 centrosomal protein 57kDa 2.90272
IL18RAP interleukin 18 receptor accessory protein 2.87979
TOMM34 translocase of outer mitochondrial membrane 34 2.87518
PTK2 protein tyrosine kinase 2 2.86773
MVP major vault protein 2.85984
EIF5A2 eukaryotic translation initiation factor 5A2 2.83787
IL4R interleukin 4 receptor 2.83542
YOD1 YOD1 deubiquitinase 2.83132
TPBG trophoblast glycoprotein 2.83044
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 2.81643
CIAO3 cytosolic iron-sulfur assembly component 3 2.81445
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 2.81371
TES testin LIM domain protein 2.80783
NRBP1 nuclear receptor binding protein 1 2.79853
DLX5 distal-less homeobox 5 2.78543
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 2.77645
UPP1 uridine phosphorylase 1 2.76603
ECD ecdysoneless homolog (Drosophila) 2.75359
KLHL21 kelch-like family member 21 2.75217
MGAM maltase-glucoamylase 2.75118
CYSLTR1 cysteinyl leukotriene receptor 1 2.7447
HOXA2 homeobox A2 2.74414
ANO1 anoctamin 1, calcium activated chloride channel 2.74407
NRDE2 NRDE-2, necessary for RNA interference, domain containing 2.74026
GUK1 guanylate kinase 1 2.7385
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 2.73768
TP73 tumor protein p73 2.72765
TLR1 toll-like receptor 1 2.72363
GARRE1 granule associated Rac and RHOG effector 1 2.71648
H1-2 H1.2 linker histone, cluster member 2.71614
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 2.70315
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 2.68838
GATA2 GATA binding protein 2 2.68837
HABP2 hyaluronan binding protein 2 2.66737
MMP2 matrix metallopeptidase 2 2.66341
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 2.65919
TDP2 tyrosyl-DNA phosphodiesterase 2 2.6574
MMP1 matrix metallopeptidase 1 2.65703
ZNF225 zinc finger protein 225 2.65037
FKBP4 FK506 binding protein 4, 59kDa 2.6364
PMM2 phosphomannomutase 2 2.62828
KCNK5 potassium channel, two pore domain subfamily K, member 5 2.6266
NXF3 nuclear RNA export factor 3 2.62485
IL5 interleukin 5 2.61687
PTPRF protein tyrosine phosphatase, receptor type, F 2.60294
H2BC6 H2B clustered histone 6 2.59972
GSTA1 glutathione S-transferase alpha 1 2.59419
ZNF34 zinc finger protein 34 2.58134
FGFR2 fibroblast growth factor receptor 2 2.57781
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 2.57511
BYSL bystin-like 2.5749
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 2.57313
ANKRD36C ankyrin repeat domain 36C 2.56069
STX4 syntaxin 4 2.55195
CCL1 chemokine (C-C motif) ligand 1 2.54529
RALB v-ral simian leukemia viral oncogene homolog B 2.53926
PTPN7 protein tyrosine phosphatase, non-receptor type 7 2.53533
EN1 engrailed homeobox 1 2.53358
DVL3 dishevelled segment polarity protein 3 2.53354
MUC1 mucin 1, cell surface associated 2.52261
IL1B interleukin 1, beta 2.52073
GSTA3 glutathione S-transferase alpha 3 2.51402
DGKA diacylglycerol kinase, alpha 80kDa 2.51179
ELF4 E74-like factor 4 (ets domain transcription factor) 2.50947
LARP6 La ribonucleoprotein domain family, member 6 2.5004
ZNF155 zinc finger protein 155 2.49665
NHLH2 nescient helix loop helix 2 2.4907
PDE9A phosphodiesterase 9A 2.49016
FOSB FBJ murine osteosarcoma viral oncogene homolog B 2.48941
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 2.48085
ANKRD10 ankyrin repeat domain 10 2.47996
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 2.47877
LYN LYN proto-oncogene, Src family tyrosine kinase 2.47821
MBOAT7 membrane bound O-acyltransferase domain containing 7 2.47768
PPY pancreatic polypeptide 2.47651
ZNF362 zinc finger protein 362 2.47523
AHNAK2 AHNAK nucleoprotein 2 2.47443
RGL2 ral guanine nucleotide dissociation stimulator-like 2 2.45499
JOSD1 Josephin domain containing 1 2.45103
PRDM13 PR domain containing 13 2.44683
XPO7 exportin 7 2.44365
UST uronyl-2-sulfotransferase 2.44242
MOB3B MOB kinase activator 3B 2.44043
IL18 interleukin 18 2.43386
ARL4C ADP-ribosylation factor-like 4C 2.43203
TSPAN2 tetraspanin 2 2.42004
HPSE heparanase 2.41507
TMEM156 transmembrane protein 156 2.41285
GRB7 growth factor receptor-bound protein 7 2.41139
KLF7 Kruppel-like factor 7 (ubiquitous) 2.40884
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 2.40745
CAMTA2 calmodulin binding transcription activator 2 2.40652
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 2.38892
ZNF227 zinc finger protein 227 2.38554
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 2.37984
CASP4 caspase 4, apoptosis-related cysteine peptidase 2.37536
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 2.36989
ZNF154 zinc finger protein 154 2.36489
DENND1B DENN/MADD domain containing 1B 2.36465
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 2.36131
JMJD6 jumonji domain containing 6 2.36084
ADAP2 ArfGAP with dual PH domains 2 2.35553
ODR4 odr-4 GPCR localization factor homolog 2.34706
RTL8A retrotransposon Gag like 8A 2.34691
LPAR2 lysophosphatidic acid receptor 2 2.34013
SNX7 sorting nexin 7 2.33966
KAT2B K(lysine) acetyltransferase 2B 2.32957
ARMC1 armadillo repeat containing 1 2.32783
MBTD1 mbt domain containing 1 2.32017
FRS2 fibroblast growth factor receptor substrate 2 2.31877
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 2.31156
RPP38 ribonuclease P/MRP 38kDa subunit 2.30543
DSE dermatan sulfate epimerase 2.30237
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.29852
ASCC1 activating signal cointegrator 1 complex subunit 1 2.29575
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 2.29366
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 2.2889
NUP58 nucleoporin 58 2.28677
AADAC arylacetamide deacetylase 2.27362
TP53BP2 tumor protein p53 binding protein 2 2.26989
ULK1 unc-51 like autophagy activating kinase 1 2.26872
ELOVL4 ELOVL fatty acid elongase 4 2.26615
TREM1 triggering receptor expressed on myeloid cells 1 2.26257
PRPF3 pre-mRNA processing factor 3 2.25158
GPRASP1 G protein-coupled receptor associated sorting protein 1 2.25145
GDI1 GDP dissociation inhibitor 1 2.24542
LMBRD1 LMBR1 domain containing 1 2.2425
AATF apoptosis antagonizing transcription factor 2.24222
SOCS2 suppressor of cytokine signaling 2 2.24192
SDF4 stromal cell derived factor 4 2.24124
FANCE Fanconi anemia, complementation group E 2.24032
EZR ezrin 2.23967
CEP97 centrosomal protein 97kDa 2.23757
KHDC1L KH homology domain containing 1-like 2.23624
KCNK3 potassium channel, two pore domain subfamily K, member 3 2.23585
BRDT bromodomain, testis-specific 2.23495
GPR65 G protein-coupled receptor 65 2.23485
CXCL2 chemokine (C-X-C motif) ligand 2 2.23415
EXO5 exonuclease 5 2.2337
COL21A1 collagen, type XXI, alpha 1 2.23247
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) 2.22845
ZBTB7C zinc finger and BTB domain containing 7C 2.22405
ZBTB5 zinc finger and BTB domain containing 5 2.22404
NKX3-2 NK3 homeobox 2 2.22341
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 2.21575
FBXO28 F-box protein 28 2.21526
KLF13 Kruppel-like factor 13 2.21196
IER5 immediate early response 5 2.20991
CCDC28A coiled-coil domain containing 28A 2.20883
UBE2L6 ubiquitin-conjugating enzyme E2L 6 2.20784
KRT12 keratin 12, type I 2.20373
HOXD3 homeobox D3 2.20309
MOCS1 molybdenum cofactor synthesis 1 2.20151
RIPPLY2-CYB5R4 RIPPLY2-CYB5R4 readthrough 2.19501
GPR63 G protein-coupled receptor 63 2.19415
CCL2 chemokine (C-C motif) ligand 2 2.19112
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 2.19014
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 2.18981
UNC5B unc-5 homolog B (C. elegans) 2.18769
PPWD1 peptidylprolyl isomerase domain and WD repeat containing 1 2.1842
TJAP1 tight junction associated protein 1 (peripheral) 2.18407
TBC1D15 TBC1 domain family, member 15 2.18149
ATOSB atos homolog B 2.17702
UBE2Q1 ubiquitin-conjugating enzyme E2Q family member 1 2.17254
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 2.17243
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 2.17091
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.16771
SAYSD1 SAYSVFN motif domain containing 1 2.16093
AMIGO2 adhesion molecule with Ig-like domain 2 2.16017
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled 2.15826
ADM adrenomedullin 2.15709
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2.15558
FGF18 fibroblast growth factor 18 2.15539
NRP1 neuropilin 1 2.15213
KLRB1 killer cell lectin-like receptor subfamily B, member 1 2.15057
TCEANC2 transcription elongation factor A (SII) N-terminal and central domain containing 2 2.14492
CXCR4 chemokine (C-X-C motif) receptor 4 2.1442
CRYZL1 crystallin, zeta (quinone reductase)-like 1 2.14112
JCAD junctional cadherin 5 associated 2.13395
RAI14 retinoic acid induced 14 2.13039
CASS4 Cas scaffolding protein family member 4 2.1302
MTFR1 mitochondrial fission regulator 1 2.126
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 2.12546
PANX1 pannexin 1 2.12374
WBP2 WW domain binding protein 2 2.12033
THBD thrombomodulin 2.11847
TBCC tubulin folding cofactor C 2.11704
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1 2.11676
SNAI2 snail family zinc finger 2 2.11434
TMEM109 transmembrane protein 109 2.10877
ANXA1 annexin A1 2.10794
ANXA8L1 annexin A8-like 1 2.10712
ZNF529 zinc finger protein 529 2.10591
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 2.10385
BIRC2 baculoviral IAP repeat containing 2 2.10335
USPL1 ubiquitin specific peptidase like 1 2.10286
GDAP2 ganglioside induced differentiation associated protein 2 2.10231
DOCK10 dedicator of cytokinesis 10 2.10191
GBA1 glucosylceramidase beta 1 2.10149
GJA5 gap junction protein, alpha 5, 40kDa 2.09809
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) 2.09647
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 2.09446
TM4SF20 transmembrane 4 L six family member 20 2.09394
WLS wntless Wnt ligand secretion mediator 2.09157
ZNF280D zinc finger protein 280D 2.09072
SH3BP5 SH3-domain binding protein 5 (BTK-associated) 2.08973
ZNF549 zinc finger protein 549 2.08502
KIAA0408 KIAA0408 2.08309
FANCG Fanconi anemia, complementation group G 2.08153
RTN2 reticulon 2 2.08148
TMEM19 transmembrane protein 19 2.08102
MARK2 MAP/microtubule affinity-regulating kinase 2 2.07969
SPINT1 serine peptidase inhibitor, Kunitz type 1 2.07234
IL15RA interleukin 15 receptor, alpha 2.07043
RIOK3 RIO kinase 3 2.07032
RPGR retinitis pigmentosa GTPase regulator 2.06752
HIC1 hypermethylated in cancer 1 2.0666
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 2.06441
CMKLR2 chemerin chemokine-like receptor 2 2.06052
PLAGL1 pleiomorphic adenoma gene-like 1 2.05934
FOXF2 forkhead box F2 2.05829
PCDH17 protocadherin 17 2.0582
KDM6B lysine (K)-specific demethylase 6B 2.05764
CLEC5A C-type lectin domain family 5, member A 2.05592
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 2.05535
TBP TATA box binding protein 2.05321
GHITM growth hormone inducible transmembrane protein 2.0524
NIBAN1 niban apoptosis regulator 1 2.05152
UBE2W ubiquitin-conjugating enzyme E2W (putative) 2.0515
H1-5 H1.5 linker histone, cluster member 2.04815
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 2.04654
TEX12 testis expressed 12 2.04567
PTTG2 pituitary tumor-transforming 2 2.04518
PLCE1 phospholipase C, epsilon 1 2.04503
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17 2.04231
CLCA4 chloride channel accessory 4 2.04144
PI3 peptidase inhibitor 3, skin-derived 2.04142
GJB5 gap junction protein, beta 5, 31.1kDa 2.04073
PRDM9 PR domain containing 9 2.03862
GNG12 guanine nucleotide binding protein (G protein), gamma 12 2.03851
ZNF682 zinc finger protein 682 2.03488
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 2.03392
NKIRAS2 NFKB inhibitor interacting Ras-like 2 2.03364
ZNF804A zinc finger protein 804A 2.03288
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 2.03253
ATP8B4 ATPase, class I, type 8B, member 4 2.02749
MED17 mediator complex subunit 17 2.02217
PRTN3 proteinase 3 2.01978
CCDC121 coiled-coil domain containing 121 2.01647
WIPF1 WAS/WASL interacting protein family, member 1 2.0157
IL12A interleukin 12A 2.01255
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.01147
SOWAHC sosondowah ankyrin repeat domain family member C 2.01062
TEP1 telomerase-associated protein 1 2.00746
NEUROG2 neurogenin 2 2.00363
NABP1 nucleic acid binding protein 1 2.00272
RTCA RNA 3'-terminal phosphate cyclase 2.00192
CCNL1 cyclin L1 2.0019

decreased expression

Symbol Name Standardized Value
ETFB electron-transfer-flavoprotein, beta polypeptide -10.0
PCCB propionyl CoA carboxylase, beta polypeptide -9.86496
B4GAT1 beta-1,4-glucuronyltransferase 1 -8.3553
PYCR1 pyrroline-5-carboxylate reductase 1 -7.71821
TARBP1 TAR (HIV-1) RNA binding protein 1 -7.32725
KDM3A lysine (K)-specific demethylase 3A -6.10008
PECR peroxisomal trans-2-enoyl-CoA reductase -6.04806
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -5.89012
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -5.57683
NISCH nischarin -5.19981
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -5.13927
ARFIP2 ADP-ribosylation factor interacting protein 2 -5.10958
GNAS GNAS complex locus -5.06672
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -5.02124
CCNA2 cyclin A2 -4.95196
LBR lamin B receptor -4.9099
SOAT2 sterol O-acyltransferase 2 -4.90491
NCK1 NCK adaptor protein 1 -4.80267
TRAP1 TNF receptor-associated protein 1 -4.75361
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -4.68465
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -4.66441
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -4.64218
PGM1 phosphoglucomutase 1 -4.50453
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -4.41874
LOC124907782 dual specificity protein phosphatase 22 -4.40903
TOP2A topoisomerase (DNA) II alpha 170kDa -4.35367
HEATR1 HEAT repeat containing 1 -4.31936
TM9SF3 transmembrane 9 superfamily member 3 -4.30342
SKIC2 SKI2 subunit of superkiller complex -4.28572
CDC20 cell division cycle 20 -4.2841
C2CD5 C2 calcium-dependent domain containing 5 -4.27713
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -4.27358
ZW10 zw10 kinetochore protein -4.21683
THAP11 THAP domain containing 11 -4.20381
CDK1 cyclin-dependent kinase 1 -4.15976
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 -4.10937
NIPSNAP1 nipsnap homolog 1 (C. elegans) -4.03422
PLK1 polo-like kinase 1 -4.0047
TSPAN4 tetraspanin 4 -4.00112
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -3.95725
ISOC1 isochorismatase domain containing 1 -3.90666
LDHD lactate dehydrogenase D -3.78221
COG7 component of oligomeric golgi complex 7 -3.73588
COG2 component of oligomeric golgi complex 2 -3.72335
TCTN1 tectonic family member 1 -3.72262
MRPS16 mitochondrial ribosomal protein S16 -3.70913
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -3.67499
CCNB1 cyclin B1 -3.67422
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -3.66714
GLOD4 glyoxalase domain containing 4 -3.66121
C5 complement component 5 -3.63362
MRPL12 mitochondrial ribosomal protein L12 -3.60848
USP6NL USP6 N-terminal like -3.5798
ZDHHC6 zinc finger, DHHC-type containing 6 -3.57012
DERA deoxyribose-phosphate aldolase (putative) -3.5623
UBE3C ubiquitin protein ligase E3C -3.55826
TBC1D16 TBC1 domain family, member 16 -3.53124
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -3.51151
WDR7 WD repeat domain 7 -3.49109
GAA glucosidase, alpha; acid -3.39307
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -3.36166
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -3.32274
FAT1 FAT atypical cadherin 1 -3.28967
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.28287
DNM1L dynamin 1-like -3.23501
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -3.22939
CD320 CD320 molecule -3.21254
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -3.19621
SPDEF SAM pointed domain containing ETS transcription factor -3.19082
TXNDC9 thioredoxin domain containing 9 -3.18189
AZGP1 alpha-2-glycoprotein 1, zinc-binding -3.17986
ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 -3.17613
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.16283
R3HDM2 R3H domain containing 2 -3.15603
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -3.14952
RPS4Y1 ribosomal protein S4, Y-linked 1 -3.11282
PLS1 plastin 1 -3.09615
MTCH2 mitochondrial carrier 2 -3.07796
AKAP8 A kinase (PRKA) anchor protein 8 -3.07752
FGFR4 fibroblast growth factor receptor 4 -3.04267
ERBB2 erb-b2 receptor tyrosine kinase 2 -3.04204
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -3.01494
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -3.01252
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -2.9902
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9 -2.98161
PGAM4 phosphoglycerate mutase family member 4 -2.92334
MRPL23 mitochondrial ribosomal protein L23 -2.91237
STK25 serine/threonine kinase 25 -2.87136
COPB1 coatomer protein complex, subunit beta 1 -2.84503
NUP85 nucleoporin 85kDa -2.84155
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.83277
INTS3 integrator complex subunit 3 -2.82378
NEK4 NIMA-related kinase 4 -2.80868
MAGED1 melanoma antigen family D1 -2.74138
SIRT3 sirtuin 3 -2.73313
ATP7B ATPase, Cu++ transporting, beta polypeptide -2.72256
UROS uroporphyrinogen III synthase -2.72154
PSRC1 proline/serine-rich coiled-coil 1 -2.7195
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.71257
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 -2.70918
HMG20B high mobility group 20B -2.69562
KLHDC4 kelch domain containing 4 -2.6769
SLC35B1 solute carrier family 35, member B1 -2.67174
TWF2 twinfilin actin binding protein 2 -2.67104
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -2.66776
CDKN3 cyclin-dependent kinase inhibitor 3 -2.65757
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.64991
MRPL35 mitochondrial ribosomal protein L35 -2.6479
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -2.64532
PXMP2 peroxisomal membrane protein 2, 22kDa -2.64344
LARS2 leucyl-tRNA synthetase 2, mitochondrial -2.63774
AURKB aurora kinase B -2.63455
PDIA5 protein disulfide isomerase family A, member 5 -2.6335
NGRN neugrin, neurite outgrowth associated -2.62938
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -2.62758
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.61994
LRBA LPS-responsive vesicle trafficking, beach and anchor containing -2.6163
ERBB3 erb-b2 receptor tyrosine kinase 3 -2.60528
METTL9 methyltransferase like 9 -2.60042
PROS1 protein S (alpha) -2.59987
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta -2.59957
MYC v-myc avian myelocytomatosis viral oncogene homolog -2.59792
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.5964
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -2.59329
TATDN2 TatD DNase domain containing 2 -2.57994
ENDOG endonuclease G -2.57675
AURKA aurora kinase A -2.57178
POLR3K polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa -2.57135
TUFM Tu translation elongation factor, mitochondrial -2.55271
RPIA ribose 5-phosphate isomerase A -2.55159
FDFT1 farnesyl-diphosphate farnesyltransferase 1 -2.54984
FBXO31 F-box protein 31 -2.54762
NCAPG2 non-SMC condensin II complex, subunit G2 -2.54753
PEBP1 phosphatidylethanolamine binding protein 1 -2.54036
SP3 Sp3 transcription factor -2.53729
CCP110 centriolar coiled coil protein 110kDa -2.52787
BPIFA1 BPI fold containing family A, member 1 -2.52141
NFIL3 nuclear factor, interleukin 3 regulated -2.52024
SRSF9 serine/arginine-rich splicing factor 9 -2.51938
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.50803
PLOD3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 -2.50253
HMGA2 high mobility group AT-hook 2 -2.50199
TARBP2 TAR (HIV-1) RNA binding protein 2 -2.49964
IQGAP2 IQ motif containing GTPase activating protein 2 -2.49545
FKBP3 FK506 binding protein 3, 25kDa -2.49389
ENOPH1 enolase-phosphatase 1 -2.47262
PCNA proliferating cell nuclear antigen -2.47249
NNT nicotinamide nucleotide transhydrogenase -2.4666
CDK4 cyclin-dependent kinase 4 -2.452
ALG6 ALG6, alpha-1,3-glucosyltransferase -2.44236
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) -2.44055
TMEM97 transmembrane protein 97 -2.43156
MNAT1 MNAT CDK-activating kinase assembly factor 1 -2.42933
CA5A carbonic anhydrase VA, mitochondrial -2.41414
TBC1D10C TBC1 domain family, member 10C -2.41357
TTC38 tetratricopeptide repeat domain 38 -2.40511
PRAF2 PRA1 domain family, member 2 -2.40324
CERS1 ceramide synthase 1 -2.39803
ACSL3 acyl-CoA synthetase long-chain family member 3 -2.39452
RBM14-RBM4 RBM14-RBM4 readthrough -2.3888
ISOC2 isochorismatase domain containing 2 -2.38795
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) -2.36318
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.35562
KIF14 kinesin family member 14 -2.35517
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.3523
PIGN phosphatidylinositol glycan anchor biosynthesis, class N -2.34074
RBBP4 retinoblastoma binding protein 4 -2.33873
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -2.33304
NAV2 neuron navigator 2 -2.3311
NUP93 nucleoporin 93kDa -2.32057
STAT1 signal transducer and activator of transcription 1, 91kDa -2.31096
CRYZ crystallin, zeta (quinone reductase) -2.30651
SLC29A2 solute carrier family 29 (equilibrative nucleoside transporter), member 2 -2.30227
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.29911
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -2.29183
DCXR dicarbonyl/L-xylulose reductase -2.289
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -2.28858
ATP5PD ATP synthase peripheral stalk subunit d -2.27826
ANAPC1 anaphase promoting complex subunit 1 -2.27553
CTR9 CTR9, Paf1/RNA polymerase II complex component -2.27169
NPY neuropeptide Y -2.26865
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -2.26229
SAA4 serum amyloid A4, constitutive -2.25249
HDAC2 histone deacetylase 2 -2.24624
APOD apolipoprotein D -2.24546
ADAM10 ADAM metallopeptidase domain 10 -2.23966
PROX1 prospero homeobox 1 -2.23645
ELAVL1 ELAV like RNA binding protein 1 -2.23361
ANKRD17 ankyrin repeat domain 17 -2.23195
RAB4A RAB4A, member RAS oncogene family -2.22968
BPNT1 3'(2'), 5'-bisphosphate nucleotidase 1 -2.22663
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.22651
SIK2 salt-inducible kinase 2 -2.21802
NUP210 nucleoporin 210kDa -2.21364
NDUFA3 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa -2.21303
SYT17 synaptotagmin XVII -2.21097
WASHC4 WASH complex subunit 4 -2.20767
GCAT glycine C-acetyltransferase -2.20296
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 -2.20287
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 -2.19735
CHEK2 checkpoint kinase 2 -2.19637
SNRPF small nuclear ribonucleoprotein polypeptide F -2.19352
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24 -2.19259
FIBP fibroblast growth factor (acidic) intracellular binding protein -2.18695
ATP5MC3 ATP synthase membrane subunit c locus 3 -2.1812
DCPS decapping enzyme, scavenger -2.17656
SLC45A2 solute carrier family 45, member 2 -2.175
CLIC4 chloride intracellular channel 4 -2.17169
TMEM33 transmembrane protein 33 -2.17158
GTPBP8 GTP-binding protein 8 (putative) -2.17082
SLC16A6 solute carrier family 16, member 6 -2.16764
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -2.16497
XPO1 exportin 1 -2.16399
HADH hydroxyacyl-CoA dehydrogenase -2.16302
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) -2.16269
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 -2.15211
NME4 NME/NM23 nucleoside diphosphate kinase 4 -2.1508
NANS N-acetylneuraminic acid synthase -2.14792
SCARB1 scavenger receptor class B, member 1 -2.14709
MLPH melanophilin -2.14414
ABAT 4-aminobutyrate aminotransferase -2.13319
WDR12 WD repeat domain 12 -2.1311
PGAP2 post-GPI attachment to proteins 2 -2.13048
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) -2.13016
CADPS2 Ca++-dependent secretion activator 2 -2.12892
CHPT1 choline phosphotransferase 1 -2.12428
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 -2.12394
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -2.1238
MADD MAP-kinase activating death domain -2.11872
ZNF106 zinc finger protein 106 -2.1089
PRPF4 pre-mRNA processing factor 4 -2.10859
DHRS4 dehydrogenase/reductase (SDR family) member 4 -2.10564
TOP2B topoisomerase (DNA) II beta 180kDa -2.1033
PDF peptide deformylase (mitochondrial) -2.10256
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 -2.10072
AACS acetoacetyl-CoA synthetase -2.09745
AP1AR adaptor-related protein complex 1 associated regulatory protein -2.09634
COX5B cytochrome c oxidase subunit Vb -2.09211
PYGL phosphorylase, glycogen, liver -2.09178
PNKP polynucleotide kinase 3'-phosphatase -2.08821
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal -2.08797
GCDH glutaryl-CoA dehydrogenase -2.08778
NTM neurotrimin -2.08513
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.08384
ALX1 ALX homeobox 1 -2.08276
DEAF1 DEAF1 transcription factor -2.07521
SOSTDC1 sclerostin domain containing 1 -2.07405
CAPN7 calpain 7 -2.07375
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -2.07313
USF2 upstream transcription factor 2, c-fos interacting -2.07287
RLIG1 RNA 5'-phosphate and 3'-OH ligase 1 -2.0678
GLT8D1 glycosyltransferase 8 domain containing 1 -2.06291
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.0575
NUP133 nucleoporin 133kDa -2.05325
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 -2.05002
NT5DC2 5'-nucleotidase domain containing 2 -2.04687
RPS5 ribosomal protein S5 -2.04678
SPTSSA serine palmitoyltransferase, small subunit A -2.04633
TYR tyrosinase -2.04623
SCCPDH saccharopine dehydrogenase (putative) -2.04598
GMDS GDP-mannose 4,6-dehydratase -2.04177
IGSF1 immunoglobulin superfamily, member 1 -2.03028
GMPPA GDP-mannose pyrophosphorylase A -2.02929
QPRT quinolinate phosphoribosyltransferase -2.02782
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa -2.02127
WDR77 WD repeat domain 77 -2.01949
PFAS phosphoribosylformylglycinamidine synthase -2.01929
HAT1 histone acetyltransferase 1 -2.01542
RGS2 regulator of G-protein signaling 2 -2.01203
RAB15 RAB15, member RAS oncogene family -2.0114
BIRC5 baculoviral IAP repeat containing 5 -2.00734
GDE1 glycerophosphodiester phosphodiesterase 1 -2.00397
SLC66A2 solute carrier family 66 member 2 -2.0031