CRCGN013_HEPG2_24H:B16 Gene Set
Genes
45 genes differentially expressed following the CRCGN013_HEPG2_24H:B16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
5.1904
|
|
LCN2
|
lipocalin 2
|
4.85902
|
|
TATDN2
|
TatD DNase domain containing 2
|
4.34682
|
|
EPN2
|
epsin 2
|
3.57614
|
|
CCNF
|
cyclin F
|
3.48696
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.41737
|
|
ABHD4
|
abhydrolase domain containing 4
|
3.01284
|
|
MYLK
|
myosin light chain kinase
|
2.98677
|
|
CCNH
|
cyclin H
|
2.92215
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.90191
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
2.86612
|
|
CHN1
|
chimerin 1
|
2.78433
|
|
SQOR
|
sulfide quinone oxidoreductase
|
2.71816
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.66728
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.62493
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
2.5539
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.39194
|
|
GPATCH8
|
G patch domain containing 8
|
2.33071
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.26861
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.2326
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.23206
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
2.1583
|
|
CETN3
|
centrin, EF-hand protein, 3
|
2.14625
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.09475
|
|
ZNF706
|
zinc finger protein 706
|
2.08794
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.03454
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-9.55015
|
|
LDHD
|
lactate dehydrogenase D
|
-7.63531
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-6.66504
|
|
DNM1L
|
dynamin 1-like
|
-5.43408
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.08936
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.73948
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-4.34664
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-4.22514
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.67295
|
|
HMG20B
|
high mobility group 20B
|
-3.01712
|
|
ZNF586
|
zinc finger protein 586
|
-2.78709
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-2.76053
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
-2.73882
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-2.73458
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.41983
|
|
ISOC1
|
isochorismatase domain containing 1
|
-2.34689
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.29902
|
|
ADA
|
adenosine deaminase
|
-2.27614
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
-2.17788
|
