CRCGN013_HEPG2_24H:B18 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description p-nitrosodiphenylamine 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

35 genes differentially expressed following the CRCGN013_HEPG2_24H:B18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 7.53045
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 6.93117
CXCR4 chemokine (C-X-C motif) receptor 4 6.31012
SSBP2 single-stranded DNA binding protein 2 5.47045
NOTCH1 notch 1 4.92866
CHN1 chimerin 1 4.92592
STIMATE STIM activating enhancer 3.98721
MAP7 microtubule-associated protein 7 3.87938
LCN2 lipocalin 2 3.6028
SFTPB surfactant protein B 3.37343
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.36492
FCHO1 FCH domain only 1 3.2234
EGF epidermal growth factor 2.99366
LPAR2 lysophosphatidic acid receptor 2 2.75434
AMDHD2 amidohydrolase domain containing 2 2.56058
MNAT1 MNAT CDK-activating kinase assembly factor 1 2.55539
TREM1 triggering receptor expressed on myeloid cells 1 2.32413
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.24587
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 2.16912
CEP57 centrosomal protein 57kDa 2.08914
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3 2.06509

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -7.55227
VAT1 vesicle amine transport 1 -5.46567
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -5.2604
NISCH nischarin -4.76868
NGRN neugrin, neurite outgrowth associated -4.24514
PCNA proliferating cell nuclear antigen -3.69407
RAI14 retinoic acid induced 14 -3.18987
SNX11 sorting nexin 11 -2.61433
MAPK3 mitogen-activated protein kinase 3 -2.34867
RSAD1 radical S-adenosyl methionine domain containing 1 -2.24887
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 -2.19286
PECR peroxisomal trans-2-enoyl-CoA reductase -2.13108
HMGN4 high mobility group nucleosomal binding domain 4 -2.10443
TRPM8 transient receptor potential cation channel, subfamily M, member 8 -2.02732