CRCGN013_HEPG2_24H:B21 Gene Set
Genes
57 genes differentially expressed following the CRCGN013_HEPG2_24H:B21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
5.39232
|
|
STK10
|
serine/threonine kinase 10
|
5.35344
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
4.5787
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.28932
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.23086
|
|
GNAI2
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
|
4.1458
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.96125
|
|
CHN1
|
chimerin 1
|
3.78887
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.65272
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
3.54099
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
3.53247
|
|
CCNF
|
cyclin F
|
3.35943
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.30659
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.85406
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.75149
|
|
EPHA3
|
EPH receptor A3
|
2.74283
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.64507
|
|
JADE2
|
jade family PHD finger 2
|
2.64366
|
|
EGF
|
epidermal growth factor
|
2.58208
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.56875
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.1575
|
|
FBN1
|
fibrillin 1
|
2.07797
|
|
FGR
|
FGR proto-oncogene, Src family tyrosine kinase
|
2.02245
|
|
SERPINE1
|
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
|
2.00362
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GNAS
|
GNAS complex locus
|
-7.03942
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-5.17483
|
|
LDHD
|
lactate dehydrogenase D
|
-5.02566
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.59773
|
|
CCNB2
|
cyclin B2
|
-4.57455
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.55264
|
|
YME1L1
|
YME1-like 1 ATPase
|
-4.47911
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.45577
|
|
TRAP1
|
TNF receptor-associated protein 1
|
-3.88222
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.78181
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
-3.73957
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.56527
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.55278
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-3.39263
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.19769
|
|
RPS5
|
ribosomal protein S5
|
-3.02168
|
|
DCK
|
deoxycytidine kinase
|
-2.81241
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.79045
|
|
UPF2
|
UPF2 regulator of nonsense transcripts homolog (yeast)
|
-2.61239
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.54084
|
|
AKIRIN1
|
akirin 1
|
-2.40892
|
|
AKAP8
|
A kinase (PRKA) anchor protein 8
|
-2.37348
|
|
CAB39
|
calcium binding protein 39
|
-2.29226
|
|
BLCAP
|
bladder cancer associated protein
|
-2.25264
|
|
HBZ
|
hemoglobin, zeta
|
-2.2225
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
-2.18513
|
|
TMOD1
|
tropomodulin 1
|
-2.14723
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.12767
|
|
HMG20B
|
high mobility group 20B
|
-2.10282
|
|
MALT1
|
MALT1 paracaspase
|
-2.08967
|
|
EEF1E1
|
eukaryotic translation elongation factor 1 epsilon 1
|
-2.04745
|
|
RPS11
|
ribosomal protein S11
|
-2.03876
|
|
SSR4
|
signal sequence receptor, delta
|
-2.00675
|
