CRCGN013_HEPG2_24H:B22 Gene Set
Genes
42 genes differentially expressed following the CRCGN013_HEPG2_24H:B22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
6.90586
|
|
MOK
|
MOK protein kinase
|
5.02926
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.89022
|
|
GPATCH8
|
G patch domain containing 8
|
4.88956
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
4.79723
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.70301
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.42261
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
4.20634
|
|
TBP
|
TATA box binding protein
|
3.69986
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.55493
|
|
KIF5C
|
kinesin family member 5C
|
3.38428
|
|
VGLL4
|
vestigial-like family member 4
|
3.36425
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.02158
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.83731
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
2.76434
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.40568
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.39876
|
|
SEC13
|
SEC13 homolog (S. cerevisiae)
|
2.31744
|
|
PMM2
|
phosphomannomutase 2
|
2.29119
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.28035
|
|
EGF
|
epidermal growth factor
|
2.1592
|
|
TMEM147
|
transmembrane protein 147
|
2.1458
|
|
COL11A1
|
collagen, type XI, alpha 1
|
2.10278
|
|
TSPYL4
|
TSPY-like 4
|
2.02557
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MAPK13
|
mitogen-activated protein kinase 13
|
-7.22985
|
|
LDHD
|
lactate dehydrogenase D
|
-6.18468
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-5.14982
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.65491
|
|
CCNB1
|
cyclin B1
|
-4.13821
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.40399
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
-3.39468
|
|
COG4
|
component of oligomeric golgi complex 4
|
-3.36596
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-3.29412
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.23182
|
|
RAI14
|
retinoic acid induced 14
|
-2.87622
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.85965
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
-2.79144
|
|
MAOA
|
monoamine oxidase A
|
-2.30092
|
|
DRAP1
|
DR1-associated protein 1 (negative cofactor 2 alpha)
|
-2.25849
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.25302
|
|
TYROBP
|
TYRO protein tyrosine kinase binding protein
|
-2.14153
|
|
RRAS2
|
related RAS viral (r-ras) oncogene homolog 2
|
-2.10484
|
