CRCGN013_HEPG2_24H:B23 Gene Set
Genes
48 genes differentially expressed following the CRCGN013_HEPG2_24H:B23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STK10
|
serine/threonine kinase 10
|
5.49139
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
5.42851
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
4.72134
|
|
MSRA
|
methionine sulfoxide reductase A
|
3.70488
|
|
GATA3
|
GATA binding protein 3
|
3.47699
|
|
CHN1
|
chimerin 1
|
3.37533
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.2854
|
|
SFTPB
|
surfactant protein B
|
3.24698
|
|
EVL
|
Enah/Vasp-like
|
3.23006
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.20951
|
|
LCN2
|
lipocalin 2
|
3.15576
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.0822
|
|
PMM2
|
phosphomannomutase 2
|
3.06557
|
|
TBP
|
TATA box binding protein
|
2.87842
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.73184
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.71155
|
|
CRTAP
|
cartilage associated protein
|
2.68518
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.67031
|
|
MTNAP1
|
mitochondrial nucleoid associated protein 1
|
2.33751
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.26779
|
|
WDR19
|
WD repeat domain 19
|
2.20334
|
|
CCL4
|
chemokine (C-C motif) ligand 4
|
2.13908
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.06215
|
|
GZMH
|
granzyme H (cathepsin G-like 2, protein h-CCPX)
|
2.06168
|
|
KLRG1
|
killer cell lectin-like receptor subfamily G, member 1
|
2.05153
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
2.03531
|
|
CEP97
|
centrosomal protein 97kDa
|
2.01352
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLCD3A
|
TLC domain containing 3A
|
-5.48928
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.34433
|
|
NUP93
|
nucleoporin 93kDa
|
-5.03097
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.0
|
|
GDF15
|
growth differentiation factor 15
|
-5.0
|
|
LDHD
|
lactate dehydrogenase D
|
-4.87239
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.8351
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.66864
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-4.66547
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.62889
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.79646
|
|
CDC20
|
cell division cycle 20
|
-3.66143
|
|
CCNB1
|
cyclin B1
|
-3.50421
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.13251
|
|
ZNF274
|
zinc finger protein 274
|
-2.91397
|
|
EGF
|
epidermal growth factor
|
-2.72838
|
|
TCTA
|
T-cell leukemia translocation altered
|
-2.38267
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.37384
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.26286
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.17912
|
|
BEST1
|
bestrophin 1
|
-2.16163
|
