| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | caffeine 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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51 genes differentially expressed following the CRCGN013_HEPG2_24H:B24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 | 7.05808 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 5.10646 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.48885 |
| SOCS2 | suppressor of cytokine signaling 2 | 4.12028 |
| ZNF589 | zinc finger protein 589 | 4.05774 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.94563 |
| LCN2 | lipocalin 2 | 3.8226 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 3.77638 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.74058 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 3.55089 |
| E2F2 | E2F transcription factor 2 | 3.49201 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.36112 |
| UBQLN2 | ubiquilin 2 | 3.20831 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.95201 |
| CHN1 | chimerin 1 | 2.86649 |
| RRAGA | Ras-related GTP binding A | 2.7956 |
| TXNL4B | thioredoxin-like 4B | 2.76679 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 2.73809 |
| FPGS | folylpolyglutamate synthase | 2.4488 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.37957 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 2.30635 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 2.24036 |
| MOK | MOK protein kinase | 2.22537 |
| RUNDC3B | RUN domain containing 3B | 2.08159 |
| PLSCR1 | phospholipid scramblase 1 | 2.01035 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -5.26471 |
| GTPBP8 | GTP-binding protein 8 (putative) | -3.9805 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.91613 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.68144 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.65789 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.60506 |
| THAP11 | THAP domain containing 11 | -3.47831 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.29757 |
| SLC35F2 | solute carrier family 35, member F2 | -3.18263 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -3.05729 |
| VDAC1 | voltage-dependent anion channel 1 | -2.9828 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.95707 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.95154 |
| COG4 | component of oligomeric golgi complex 4 | -2.82078 |
| CDC20 | cell division cycle 20 | -2.73868 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.60166 |
| ILK | integrin-linked kinase | -2.451 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.35931 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -2.28589 |
| TLCD3A | TLC domain containing 3A | -2.27997 |
| CCNB2 | cyclin B2 | -2.16218 |
| TXNDC9 | thioredoxin domain containing 9 | -2.14917 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.14298 |
| GNAS | GNAS complex locus | -2.07606 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 | -2.06345 |
| PSMD9 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 | -2.04871 |
